Several epidemiological and experimental studies have demonstrated that many human
diseases are not only caused by specific genetic and environmental factors but also by gene …

Colorectal cancer (CRC) is the third most common cancer and has the second highest
cancer-related mortality in the world. The incident rates of CRC vary country-wise; however …

PURPOSE Given the increasing incidence of early-onset colorectal cancer (CRC;
diagnosed before age 50 years) worldwide, it is important to identify modifiable risk factors …

Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity,
including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra …

Lung adenocarcinoma (LUAD) is a common form of lung cancer. Although cisplatin
chemotherapy is an effective treatment option, some patients with LUAD can develop drug …

Colorectal cancer (CRC) is the second most deadly cancer in the whole world, with the
underlying mechanisms largely indistinct. Therefore, we aimed to identify significant …

Background Alcohol intake is a well-known lifestyle risk factor for CRC, and an increasing
number of studies have revealed that alcohol intake is also tightly associated with CRC …

There is sufficient evidence for the association between alcohol consumption and cancers of
the esophagus, stomach, colon–rectum and pancreas. Public health policies to prevent …

Background Increases in IL-6 by cancer-associated fibroblasts (CAFs) contribute to colon
cancer progression, but the mechanisms involved in the increase of this tumor-promoting …

Background Hashimoto's thyroiditis (HT) is a chronic autoimmune disease that poses a risk
factor for papillary thyroid carcinoma (PTC). The present study aimed to identify the key …