Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Cancer is a complex disease whose outcome depends largely on the cross-talk between the
tumor and its microenvironment. Here, we review the evolution of the field of tumor …

Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Mast cells are unique tissue-resident immune cells of the myeloid lineage that have long
been implicated in the pathogenesis of allergic and autoimmune disorders. More recently …

Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …

The main function of the mammalian immune system is to monitor tissue homeostasis, to
protect against invading or infectious pathogens and to eliminate damaged cells. Therefore …

The use of various transgenic mouse models and analysis of human tumour biopsies has
shown that bone marrow-derived myeloid cells, such as macrophages, neutrophils …

Recent insights into the molecular and cellular mechanisms underlying cancer development
have revealed that immune cells functionally regulate epithelial cancer development and …

BACKGROUND Natural killer (NK) cells are a group of effector cells that act nonspecifically
against tumor cells. The correlation between intratumoral NK cell infiltration and …

In addition to malignant neoplastic cells, cancer tissues also include immune cells,
fibroblasts, and endothelial cells, including an abundant collection of growth factors …