Immortalized cell lines are widely used in vitro tools in oncology and hematology research.
While these cell lines represent artificial systems and may accumulate genetic aberrations …

Abstract Until recently, 20% to 30% of pediatric B-cell precursor acute lymphoblastic
leukemia (BCP-ALL) could not be classified into any of the established molecular subtypes …

In the present investigation, we sought to refine the classification of urothelial carcinoma by
combining information on gene expression, genomic, and gene mutation levels. For these …

Mutations in DNA methyltransferase 3A (DNMT3A) are common in acute myeloid leukemia
and portend a poor prognosis; thus, new therapeutic strategies are needed. The likely …

Gene expression analyses were performed on 121 consecutive childhood leukemias (87 B-
lineage acute lymphoblastic leukemias (ALLs), 11 T-cell ALLs and 23 acute myeloid …

Acute myeloid leukemia (AML) is the most common and severe form of acute leukemia
diagnosed in adults. Owing to its heterogeneity, AML is divided into classes associated with …

A BAC‐array platform for comparative genomic hybridization was constructed from a library
of 32,433 clones providing complete genome coverage, and evaluated by screening for …

Abstract Lysine-specific demethylase 1 (KDM1A) is a transcriptional coregulator that can
function in both the activation and repression of gene expression, depending upon context …

Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk
subtype of B-ALL often associated with genetic variants that alter cytokine receptor …

Purpose To identify gene expression patterns and interaction networks related to BCR-ABL
status and clinical outcome in adults with acute lymphoblastic leukemia (ALL). Patients and …