Importance Recent clinical and imaging studies underscore that major adverse cardiac
events (MACE) outcomes are associated not solely with severe coronary obstructions …

Coronary angiography has historically served as the gold standard for diagnosis of coronary
artery disease and guidance of percutaneous coronary intervention (PCI). Adjunctive use of …

Importance Coronary plaques that are prone to rupture and cause adverse cardiac events
are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins …

Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Ultrasound (US) is a biofavorable mechanical wave that has shown practical significance in
biomedical fields. Due to the cavitation effect, sonoluminescence, sonoporation, pyrolysis …

Abstract Lipoprotein (a)(Lp (a)) is associated with atherothrombosis through several
mechanisms, including putative antifibrinolytic properties. However, genetic association …

Optical coherence tomography (OCT) has been increasingly utilised to guide percutaneous
coronary intervention (PCI). Despite the diagnostic utility of OCT, facilitated by its high …

Background Acute coronary syndrome and sudden cardiac death are often caused by
rupture and thrombosis of lipid-rich atherosclerotic coronary plaques (known as vulnerable …

Background A noninvasive coronary CT angiography (CCTA)–based radiomics technique
may facilitate the identification of vulnerable plaques and patients at risk for future adverse …

Background In the multicenter, randomized, sham-controlled FAVOR (Comparison of
Quantitative Flow Ratio Guided and Angiography Guided Percutaneous Intervention in …