Biomedical research often focuses on properties that differentiate between diseased and
healthy tissue; one of the current focuses is elevated expression and altered localisation of …

Apoptosis is a highly complex and regulated cell death pathway that safeguards the
physiological balance between life and death. Over the past decade, the role of Ca 2+ …

A second-generation series of biscyclometalated 2-(5-aryl-thienyl)-benzimidazole and-
benzothiazole Ir (III) dppz complexes [Ir (C^ N) 2 (dppz)]+, Ir1–Ir4, were rationally designed …

Resident macrophages are tissue-specific innate immune cells acting as sentinels,
constantly patrolling their assigned tissue to maintain homeostasis, and quickly responding …

Extracellular ATP is a potent signaling molecule released from various cells throughout the
body and is intimately involved in the pathophysiological functions of the nervous system …

Primary graft dysfunction (PGD) is a severe form of acute lung injury resulting from lung
ischemia/reperfusion injury (I/R) in lung transplantation (LTx), associated with elevated post …

Simple Summary Lung cancer is the most prevalent cancer worldwide with poor overall
survival despite many new therapeutic strategies. We discuss in this review the ability of the …

Background Purinergic P2 receptors, which can be divided into ionotropic P2X receptors
and metabotropic P2Y receptors, mediate cellular signal transduction of purine or pyrimidine …

Background Alcohol, a widely abused drug, significantly diminishes life quality, causing
chronic diseases and psychiatric issues, with severe health, societal, and economic …

The host recognition of microbial products is essential for mounting an effective immune
response against invading microbes. Heptose phosphates are a novel class of bacterial …