A comprehensive insight into fungal enzymes: Structure, classification, and their role in mankind's challenges

H El-Gendi, AK Saleh, R Badierah, EM Redwan… - Journal of Fungi, 2021 - mdpi.com
Enzymes have played a crucial role in mankind's challenges to use different types of
biological systems for a diversity of applications. They are proteins that break down and …

Beneficial effects of endophytic fungi colonization on plants

L Yan, J Zhu, X Zhao, J Shi, C Jiang, D Shao - Applied microbiology and …, 2019 - Springer
Due to increasingly limited water resources, diminishing farmland acreage, and potentially
negative effects of climate change, an urgent need exists to improve agricultural productivity …

Endophytic fungi: Key insights, emerging prospects, and challenges in natural product drug discovery

P Tiwari, H Bae - Microorganisms, 2022 - mdpi.com
Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

T Isah, S Umar, A Mujib, MP Sharma… - Plant Cell, Tissue and …, 2018 - Springer
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

A critical review on exploiting the pharmaceutical potential of plant endophytic fungi

S Gupta, P Chaturvedi, MG Kulkarni… - Biotechnology advances, 2020 - Elsevier
The escalating demand for secondary metabolites in international markets poses a severe
threat to many plant species. An unscrupulous collection is also the immediate challenge to …

Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

Endophytic fungi—alternative sources of cytotoxic compounds: a review

F Uzma, CD Mohan, A Hashem, NM Konappa… - Frontiers in …, 2018 - frontiersin.org
Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …

Plant associated fungal endophytes as a source of natural bioactive compounds

N Rai, P Kumari Keshri, A Verma, SC Kamble, P Mishra… - Mycology, 2021 - Taylor & Francis
Endophytes are a potent source of bioactive compounds that mimic plant-based metabolites.
The relationship of host plant and endophyte is significantly associated with alteration in …

Bioactive secondary metabolites from endophytic fungi

E Ancheeva, G Daletos… - Current medicinal …, 2020 - ingentaconnect.com
Background: Endophytes represent a complex community of microorganisms colonizing
asymptomatically internal tissues of higher plants. Several reports have shown that …

Penicillium expansum: biology, omics, and management tools for a global postharvest pathogen causing blue mould of pome fruit

D Luciano‐Rosario, NP Keller… - Molecular Plant …, 2020 - Wiley Online Library
Blue mould, caused primarily by Penicillium expansum, is a major threat to the global pome
fruit industry, causing multimillion‐dollar losses annually. The blue mould fungus negatively …