Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …

The potent actions of pigment epithelium-derived factor (PEDF) on tumour-associated cells,
and its extracellular localization and secretion, stimulated research on this multifunctional …

Pigment epithelium-derived factor (PEDF) is a broadly expressed multifunctional member of
the serine proteinase inhibitor (serpin) family. This widely studied protein plays critical roles …

OBJECTIVE Pigment epithelium–derived factor (PEDF) is an adipocyte-secreted factor
involved in the development of insulin resistance in obesity. Previous studies have identified …

Abstract F 1 FO ATP synthase is responsible for the production of> 95% of all ATP synthesis
within the cell. Dysregulation of its expression, activity or localization is linked to various …

The directional movement of cells can be regulated by ATP, certain other nucleotides (eg,
ADP, UTP), and adenosine. Such regulation occurs for cells that are “professional …

Retinal neovascular, neurodegenerative, and inflammatory diseases represented by
diabetic retinopathy are the main types of blinding eye disorders that continually cause the …

Microvascular diseases are among the most clinically important diseases, and vascular
abnormalities are central in the development of such diseases. Pigment epithelium-derived …

Pigment epithelium-derived factor (PEDF) is a secreted glycoprotein and a non-inhibitory
member of the serine protease inhibitor (serpin) family. It is widely expressed in human fetal …

The extracellular pigment epithelium-derived factor (PEDF) displays retina survival activity
by interacting with receptor proteins on cell surfaces. We have previously reported that …