Endometrial stromal tumors of the uterus: Epidemiology, pathological and biological features, treatment options and clinical outcomes

A Gadducci, F Multinu, LA De Vitis, S Cosio… - Gynecologic …, 2023 - Elsevier
Endometrial stromal tumors (EST) are uterine mesenchymal tumors, which histologically
resemble endometrial stroma of the functioning endometrium. The majority of EST are …

NTRK and other recently described kinase fusion positive uterine sarcomas: A review of a group of rare neoplasms

S Croce, I Hostein… - Genes, Chromosomes …, 2021 - Wiley Online Library
The landscape of uterine sarcomas has greatly expanded in recent years to include
neoplasms with recurrent gene fusions, such as BCOR and YWHAE translocated high …

Impact of chemotherapy in the adjuvant setting of early stage uterine leiomyosarcoma: a systematic review and updated meta-analysis

A Rizzo, M Nannini, A Astolfi, V Indio, P De Iaco… - Cancers, 2020 - mdpi.com
Background: Although the use of adjuvant chemotherapy (AC) appears to be increasing
over the past few years, several clinical trials and previous meta-analyses failed to …

[HTML][HTML] Targeted RNA expression profiling identifies high-grade endometrial stromal sarcoma as a clinically relevant molecular subtype of uterine sarcoma

A Momeni-Boroujeni, N Mohammad, R Wolber, S Yip… - Modern Pathology, 2021 - Elsevier
High-grade endometrial stromal sarcoma (HGESS) may harbor YWHAE-NUTM2A/B fusion,
ZC3H7B-BCOR fusion, and BCOR internal tandem duplication (ITD). NTRK3 upregulation …

New aspects of sarcomas of uterine corpus—a brief narrative review

S Kostov, Y Kornovski, V Ivanova, D Dzhenkov… - Clinics and …, 2021 - mdpi.com
Sarcomas of the uterine corpus are rare malignant neoplasms, which are further classified
into mesenchymal tumors, and mixed (epithelial plus mesenchymal) tumors. The main …

Case Report: A case of COL1A1PDGFB fusion uterine sarcoma at cervix and insights into the clinical management of rare uterine sarcoma

L Lu, S Wang, H Shen, F Zhang, F Ma, Y Shi… - Frontiers in …, 2023 - frontiersin.org
COL1A1–PDGFB gene fusion uterine sarcoma is an especially rare malignant
mesenchymal tumor that was previously classified as an undifferentiated uterine sarcoma …

Novel therapeutics in the treatment of uterine sarcoma

S Bose, GK Schwartz, M Ingham - American Society of Clinical …, 2022 - ascopubs.org
Uterine sarcomas reflect the diversity of sarcoma as a whole. The most common histologies
include leiomyosarcoma, high-and low-grade endometrial stromal sarcoma, and …

[HTML][HTML] The KAT6B:: KANSL1 fusion defines a new uterine sarcoma with hybrid endometrial stromal tumor and smooth muscle tumor features

A Trecourt, R Azmani, I Hostein, L Blanchard… - Modern Pathology, 2023 - Elsevier
Neoplasms harboring a KAT6B/A:: KANSL1 fusion were initially reported as benign
(leiomyomas) and malignant (leiomyosarcomas, low-grade endometrial stromal sarcomas …

EML4–NTRK3 fusion cervical sarcoma: a case report and literature review

X Dang, T Xiang, C Zhao, H Tang, P Cui - Frontiers in Medicine, 2022 - frontiersin.org
The concept of neurotrophic factor tyrosine kinase receptor (NTRK) fusion tumor has
emerged in recent years. Moreover, NTRK fusion is unusual in common tumors but can often …

A combined radiomics and clinical variables model for prediction of malignancy in T2 hyperintense uterine mesenchymal tumors on MRI

T Wang, J Gong, Q Li, C Chu, W Shen, W Peng… - European …, 2021 - Springer
Objective This study aims to develop a machine learning model for prediction of malignancy
in T2 hyperintense mesenchymal uterine tumors based on T2-weighted image (T2WI) …