In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

Preeclampsia remains a leading cause of maternal and fetal mortality, due to ineffective
treatment and diagnostic strategies, compounded by the lack of clarity on the etiology of the …

The placenta is one of the organs with the highest evolutionary diversity among animal
species. In consequence, an animal model that reflects human placentation exactly does not …

Although the precise pathophysiology of pre-eclampsia remains unknown, this condition
continues to be a major cause of maternal and fetal mortality. Early prediction of pre …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …

Galectins are glycan-binding proteins that regulate innate and adaptive immune responses,
and some confer maternal-fetal immune tolerance in eutherian mammals. A chromosome 19 …

Exposure to particulate air pollution and socioeconomic risk factors are shown to be
independently associated with adverse pregnancy outcomes; however, their confounding …

Galectins are potent immunomodulators that regulate maternal immune responses in
pregnancy and prevent the rejection of the semi-allogeneic fetus that also occurs in …

Problem The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly
described group of molecules with a conserved structure and important immunological …

Galectins comprise a family of soluble β-galactoside-binding proteins, which regulate a
variety of key biological processes including cell growth, differentiation, survival, and death …