Dickkopf-3: current knowledge in kidney diseases

X Fang, J Hu, Y Chen, W Shen, B Ke - Frontiers in Physiology, 2020 - frontiersin.org
Dickkopf-related protein 3 (DKK3) is a secreted glycoprotein that has been implicated in the
pathogenesis of a variety of diseases. Recent evidence suggests that urinary DKK3 may …

[HTML][HTML] How Stem and Progenitor Cells Can Affect Renal Diseases

F Montenegro, F Giannuzzi, A Picerno, A Cicirelli… - Cells, 2024 - mdpi.com
Stem and progenitor cells have been observed to contribute to regenerative processes in
acute renal failure and chronic kidney disease. Recent research has delved into the intricate …

Altered Th17/Treg ratio as a possible mechanism in pathogenesis of idiopathic membranous nephropathy

R Motavalli, J Etemadi, MS Soltani-Zangbar… - Cytokine, 2021 - Elsevier
Idiopathic membranous nephropathy (IMN) as a single organ autoimmune disease is a main
cause of nephrotic syndrome in adults which is determined through autoantibodies to …

Identification of biomarkers related to immune and inflammation in membranous nephropathy: comprehensive bioinformatic analysis and validation

P Zhang, Y Geng, J Tang, Z Cao, X Xiang… - Frontiers in …, 2023 - frontiersin.org
Background Membranous nephropathy (MN) is an autoimmune glomerular disease that is
predominantly mediated by immune complex deposition and complement activation. The …

How does herbal medicine treat idiopathic membranous nephropathy?

Z Feng, W Liu, HX Jiang, H Dai, C Gao… - Frontiers in …, 2020 - frontiersin.org
Idiopathic membranous nephropathy (IMN) has made increasing progress in mechanism
and treatment research. Herbal medicine is gradually being accepted as an alternative …

Single-cell RNA sequencing shows the immune cell landscape in the kidneys of patients with idiopathic membranous nephropathy

M Shi, Y Wang, H Zhang, Z Ling, X Chen… - Frontiers in …, 2023 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is a leading pathological type of the adult
primary nephrotic syndrome. Some patients develop end-stage renal disease due to poor …

The thickness of glomerular basement membrane predicts complete remission in primary membranous nephropathy

S Duan, L Sun, C Zhang, M Zeng, B Sun, Y Yuan… - Renal …, 2023 - Taylor & Francis
Objective Glomerular basement membrane (GBM) thickening is a typical and essential
histopathological characteristic for the diagnosis of primary membranous nephropathy …

[HTML][HTML] The spatially resolved transcriptome signatures of glomeruli in chronic kidney disease

G Clair, H Soloyan, P Cravedi, A Angeletti, F Salem… - JCI insight, 2024 - ncbi.nlm.nih.gov
Here, we used digital spatial profiling (DSP) to describe the glomerular transcriptomic
signatures that may characterize the complex molecular mechanisms underlying …

Acidic Stigma maydis polysaccharides protect against podocyte injury in membranous nephropathy by maintenance of glomerular filtration barrier integrity and gut …

X Wang, Y Dong, Z Bao, S Lin - Food & Function, 2022 - pubs.rsc.org
Membranous nephropathy (MN) is a chronic kidney disease and a precursor to end-stage
kidney disease. In this study, we evaluated the potential protective effects of acidic and …

Protein energy-wasting associated with nephrotic syndrome–the comparison of metabolic pattern in severe nephrosis to different stages of chronic kidney disease

A Matyjek, S Literacki, S Niemczyk, A Rymarz - BMC nephrology, 2020 - Springer
Background Nephrotic syndrome (NS) is associated with a hypercatabolic state expressed
as an exacerbated degradation of muscle mass. However, the clinical significance of this …