It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …

Oral administration of medication is the first option when patient compliance is considered.
However, many barriers face oral absorption of drugs that limit bioavailability in about 90 …

Gingerol, one of the components of the rhizome of Ginger, has a variety of biological
activities such as anticoagulant, antioxidative, antitumor, anti-inflammatory, antihypertensive …

Diabetes is a chronic medical condition, which is characterised by high blood sugar level.
Exogenous insulin is commonly administered subcutaneously for the management of …

The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Raloxifene HCl belongs to a class of selective estrogen receptor modulators (SERMs) which
is used for the management of breast cancer. The major problem reported with raloxifene is …

Diabetes mellitus affects almost half a billion patients worldwide and results from either
destruction of β‐cells responsible for insulin secretion or increased tissue resistance to …

Raloxifene hydrochloride (RLX) shows poor bioavailability (< 2%), high inter-patient
variability and extensive gut metabolism (> 90%). The objective of this study was to develop …

The human body has long provided pharmaceutical science with biomaterials of interesting
applications. Bile salts (BSs) are biomaterials reminiscent of traditional surfactants with …

Erlotinib (ERL), a tyrosine kinase inhibitor approved for therapeutic use in non-small cell
lung cancer is further researched for eventual liver cancer treatment. However, conventional …