Vascular ageing, characterized by structural and functional changes in blood vessels of
which arterial stiffness and endothelial dysfunction are key components, is associated with …

Background To date, the mitochondrial function has been related to several pathways
involved in the cellular aging process. Dietary supplements might have reciprocal and …

BACKGROUND: Here, we assessed the role of cellular senescence and the senescence
associated secretory phenotype (SASP) in age-related aortic stiffening and endothelial …

Background: COVID-19 has become a dramatic health problem during this century. In
addition to high mortality rate, COVID-19 survivors are at increased risk for cardiovascular …

Excessive reactive oxygen species production by mitochondria (mtROS) is a key contributor
to age-related vascular endothelial dysfunction. We recently showed in a crossover design …

Under specific conditions, such as catabolic stress or systemic inflammation, endogenous
nutrient production becomes insufficient and exogenous supplementation (for example …

Consumption of a Western-style diet (WD; high fat, high sugar, low fiber) is associated with
impaired vascular function and increased risk of cardiovascular diseases (CVD), which …

Background: Cardiovascular disease (CVD) is the leading cause of death worldwide and
aging is the primary risk factor for the development of CVD. The increased risk of CVD with …

Background Dietary inorganic nitrate (NO3−) is a polyatomic ion, which is present in large
quantities in green leafy vegetables and beetroot, and has attracted considerable attention …

Vascular aging, a major risk factor for cardiovascular disease, contributes to morbidity and
mortality in older people. Mitochondria play an important role in vascular aging. In …