This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Ovarian cancer presents a significant challenge due to its high rate of chemoresistance,
which complicates the effectiveness of drug-response therapy. This study provides a …

Introduction Auranofin (AF) is a well-established, FDA-approved, antiarthritic gold drug that
is currently being reevaluated for a variety of therapeutic indications through drug …

Aurothiomalate (AuTM) is an FDA‐approved antiarthritic gold drug with unique anticancer
properties. To enhance its anticancer activity, we prepared a bioconjugate with human …

Cancer cell lines are frequently used in metabolomics, such as in vitro tumor models. In
particular, A2780 cells are commonly used as a model for ovarian cancer to evaluate the …

A combination of pathway enrichment and metabolite clustering analysis is used to interpret
untargeted 1H NMR metabolomics data, enabling a biochemically informative comparison of …

Despite the increasing interest in the development of novel metal-based compounds for
cancer treatment, these molecules are currently poorly characterized in mechanistic terms …

The role of solvent‐exposed cysteines as reactive sites for bioconjugation with a variety of
metal drugs or fluorescent probes is emerging in the use of human H‐ferritin (HuHf) as a …

Auranofin, an FDA-approved antirheumatic gold drug, has gained ongoing interest in clinical
studies for treating advanced or recurrent tumors. However, gold ion's dynamic thiol …

A descoberta das propriedades medicinais dos compostos de ouro impulsionou o design e
a síntese de novos metalo-fármacos para a terapia anticâncer. No presente trabalho …