Gastric cancer treatment: recent progress and future perspectives

WL Guan, Y He, RH Xu - Journal of hematology & oncology, 2023 - Springer
Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

Current developments in gastric cancer: from molecular profiling to treatment strategy

M Alsina, V Arrazubi, M Diez, J Tabernero - … Reviews Gastroenterology & …, 2023 - nature.com
Gastric cancer and gastro-oesophageal junction cancer represent a global health-care
challenge. Despite the efficacy of improved chemotherapy and surgical options, these …

Claudin18. 2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results

C Qi, J Gong, J Li, D Liu, Y Qin, S Ge, M Zhang… - Nature medicine, 2022 - nature.com
Despite success in hematologic malignancies, the treatment landscape of chimeric antigen
receptor (CAR) T cell therapy for solid tumors remains limited. Claudin18. 2 (CLDN18. 2) …

Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro …

YK Kang, LT Chen, MH Ryu, DY Oh, SC Oh… - The Lancet …, 2022 - thelancet.com
Background The additive or synergistic sustained antitumour effect of immune checkpoint
inhibitors in combination with oxaliplatin-based chemotherapy has previously been …

First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma …

YY Janjigian, K Shitara, M Moehler, M Garrido… - The Lancet, 2021 - thelancet.com
Background First-line chemotherapy for advanced or metastatic human epidermal growth
factor receptor 2 (HER2)-negative gastric or gastro-oesophageal junction adenocarcinoma …

Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancer

S Li, W Yu, F Xie, H Luo, Z Liu, W Lv, D Shi… - Nature …, 2023 - nature.com
Despite neoadjuvant/conversion chemotherapy, the prognosis of cT4a/bN+ gastric cancer is
poor. Immune checkpoint inhibitors (ICIs) and antiangiogenic agents have shown activity in …

Gastric cancer: a comprehensive review of current and future treatment strategies

RE Sexton, MN Al Hallak, M Diab, AS Azmi - Cancer and Metastasis …, 2020 - Springer
Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

Advances in clinical immunotherapy for gastric cancer

K Li, A Zhang, X Li, H Zhang, L Zhao - Biochimica et Biophysica Acta (BBA) …, 2021 - Elsevier
Gastric cancer (GC) is one of the most malignant human cancers with increasing incidence
worldwide, ranking among the top five malignant tumors worldwide in terms of incidence …

Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer

RJ Kelly, JA Ajani, J Kuzdzal, T Zander… - … England Journal of …, 2021 - Mass Medical Soc
Background No adjuvant treatment has been established for patients who remain at high
risk for recurrence after neoadjuvant chemoradiotherapy and surgery for esophageal or …

[HTML][HTML] Korean practice guidelines for gastric cancer 2022: an evidence-based, multidisciplinary approach

TH Kim, IH Kim, SJ Kang, M Choi, BH Kim… - Journal of gastric …, 2023 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common cancers in Korea and the world. Since 2004, this
is the 4th gastric cancer guideline published in Korea which is the revised version of …