Mitochondrial dysfunction has been implicated in the pathogenesis of almost all
neurological diseases, including Alzheimer's disease (AD). Historically, a primary focus in …

Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

This report updates previous CDC guidelines and recommendations on preferred
prevention and treatment regimens regarding naturally occurring anthrax. Also provided are …

The lack of robust treatment options available for neurodegenerative diseases, stroke, and
central nervous system (CNS) trauma, all of which often involve both inflammation and …

In the first part, the following mechanisms involved in different forms of cell death are
considered, with a view to identifying potential therapeutic targets: tumour necrosis factor …

Mood disorders are marked by high rates of non-recovery, recurrence, and chronicity, which
are insufficiently addressed by current therapies. Several patho-etiological models have …

Minocycline hydrochloride (MH), a semi-synthetic tetracycline derivative, is a clinically
available antibiotic and anti-inflammatory drug that also exhibits potent neuroprotective …

Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-
apoptotic, anti-inflammatory, and antioxidant effects. Furthermore, there is rapidly growing …

Tetracyclines are an amazing class of chemical agents with multiple therapeutic potential.
Structural modification of the original natural tetracyclines led to the synthesis and …

Mitochondria are highly dynamic organelles that serve as the primary cellular energy-
generating system. Apart from ATP production, they are essential for many biological …