Apoptosis and apoptotic body: disease message and therapeutic target potentials

X Xu, Y Lai, ZC Hua - Bioscience reports, 2019 - portlandpress.com
Apoptosis is widely known as programmed cell death eliciting no inflammatory responses.
The intricacy of apoptosis has been a focus of an array of researches, accumulating a wealth …

Updated assessment of the prevalence, spectrum and case definition of autoimmune disease

SM Hayter, MC Cook - Autoimmunity reviews, 2012 - Elsevier
Autoimmune diseases are heterogeneous with regard to prevalence, manifestations, and
pathogenesis. The classification of autoimmune diseases has varied over time. Here, we …

The ITP syndrome: pathogenic and clinical diversity

DB Cines, JB Bussel, HA Liebman… - Blood, The Journal of …, 2009 - ashpublications.org
Immune thrombocytopenia (ITP) is mediated by platelet autoantibodies that accelerate
platelet destruction and inhibit their production. Most cases are considered idiopathic …

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

JB Oliveira, JJ Bleesing, U Dianzani… - Blood, The Journal …, 2010 - ashpublications.org
Lymphadenopathy in children for which no infectious or malignant cause can be ascertained
constitutes a challenging diagnostic dilemma. Autoimmune lymphoproliferative syndrome …

Fas ligand-induced apoptosis

S Nagata - Annual review of genetics, 1999 - annualreviews.org
▪ Abstract The immune response is regulated not only by cell proliferation and differentiation,
but also by programmed cell death, or apoptosis. In response to various stimuli, death …

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

HJ Chun, L Zheng, M Ahmad, J Wang, CK Speirs… - Nature, 2002 - nature.com
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine
proteases called caspases. In the immune system, apoptosis counters the proliferation of …

The death domain superfamily in intracellular signaling of apoptosis and inflammation

HH Park, YC Lo, SC Lin, L Wang, JK Yang… - Annu. Rev …, 2007 - annualreviews.org
The death domain (DD) superfamily comprising the death domain (DD) subfamily, the death
effector domain (DED) subfamily, the caspase recruitment domain (CARD) subfamily, and …

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway

PM Chaudhary, M Eby, A Jasmin, A Bookwalter… - Immunity, 1997 - cell.com
Abstract Death receptor 4 (DR4) is a recently described receptor for the cytotoxic ligand
TRAIL that reportedly uses a FADD-independent pathway to induce apoptosis and does not …

Mature T lymphocyte apoptosis—immune regulation in a dynamic and unpredictable antigenic environment

M Lenardo, FKM Chan, F Hornung… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …

Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients

T Oyama, K Ichimura, R Suzuki… - The American journal …, 2003 - journals.lww.com
Abstract Twenty-two Epstein-Barr virus-associated B-cell lymphoproliferative disorders
(LPDs) without predisposing immunodeficiencies were evaluated clinically and …