SM Hayter, MC Cook - Autoimmunity reviews, 2012 - Elsevier
Autoimmune diseases are heterogeneous with regard to prevalence, manifestations, and pathogenesis. The classification of autoimmune diseases has varied over time. Here, we …
DB Cines, JB Bussel, HA Liebman… - Blood, The Journal of …, 2009 - ashpublications.org
Immune thrombocytopenia (ITP) is mediated by platelet autoantibodies that accelerate platelet destruction and inhibit their production. Most cases are considered idiopathic …
Lymphadenopathy in children for which no infectious or malignant cause can be ascertained constitutes a challenging diagnostic dilemma. Autoimmune lymphoproliferative syndrome …
S Nagata - Annual review of genetics, 1999 - annualreviews.org
▪ Abstract The immune response is regulated not only by cell proliferation and differentiation, but also by programmed cell death, or apoptosis. In response to various stimuli, death …
HJ Chun, L Zheng, M Ahmad, J Wang, CK Speirs… - Nature, 2002 - nature.com
Apoptosis is a form of programmed cell death that is controlled by aspartate-specific cysteine proteases called caspases. In the immune system, apoptosis counters the proliferation of …
HH Park, YC Lo, SC Lin, L Wang, JK Yang… - Annu. Rev …, 2007 - annualreviews.org
The death domain (DD) superfamily comprising the death domain (DD) subfamily, the death effector domain (DED) subfamily, the caspase recruitment domain (CARD) subfamily, and …
PM Chaudhary, M Eby, A Jasmin, A Bookwalter… - Immunity, 1997 - cell.com
Abstract Death receptor 4 (DR4) is a recently described receptor for the cytotoxic ligand TRAIL that reportedly uses a FADD-independent pathway to induce apoptosis and does not …
M Lenardo, FKM Chan, F Hornung… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and tolerance by countering the profound changes in the number and types of T cells stimulated …