The Swi2/Snf2 family ATPase Mot1 displaces TATA-binding protein (TBP) from DNA in vitro,
but the global relationship between Mot1 and TBP in vivo is unclear. In particular, how Mot1 …

A higher body weight at a younger age is an economically important trait for profitable goat
farming. This study was focused on the identification of regions of the genome that harbor …

Abstract N-ethyl-N-nitrosourea (ENU), a well known alkylating agent, is a powerful mutagen
in mouse spermatogonia that is frequently used to generate mutant mice for the study of …

Cardiogenesis and the maintenance of cardiac physiology necessitate dynamic and
carefully coordinated transcription programs. Studies in a many systems–both in vitro and in …

Osteosarcoma (OS) is one of the most malignant tumors of bone with a poor outcome in
children and young adolescents and has a poor response to radiotherapy and …

Neurulation, the early developmental process that forms the rudiment of the brain and spinal
cord, relies upon the intricate interplay of hundreds of genes in multiple genetic pathways …

Genetic defects in complex processes of embryonic development and postnatal
maintenance of the skin and its appendages result in clinically and genetically …