Mitogen synergy: an emerging route to boosting human beta cell proliferation

E Shcheglova, K Blaszczyk, M Borowiak - Frontiers in Cell and …, 2022 - frontiersin.org
Decreased number and function of beta cells are a key aspect of diabetes mellitus
(diabetes), a disease that remains an onerous global health problem. Means of restoring …

An update on RPE cell senescence as a key contributor to age-related macular degeneration: support from current and experimental treatments

MR Kozlowski - Medical hypothesis, discovery & innovation in …, 2023 - mehdijournal.com
Background: Age-related macular degeneration (AMD) is a major cause of vision loss. Its
prevalence has increased over the past decade. This increase is partly due to the scarcity of …

The anti-senescence effect of a combination using enavogliflozin, BPTES and acarbose in a type 2 diabetes animal model

홍세린 - 2024 - s-space.snu.ac.kr
The anti-senescence effect of a combination using enavogliflozin, BPTES and acarbose in a
type 2 diabetes animal model Serin Hong Major in Translational Medicine The Graduate …

Exploring beta cell NADPH production using organelle-targeted Apollo-NADP+ sensors

HHC Chang - 2023 - search.proquest.com
A major function of beta cells is the production and secretion of insulin to maintain glucose
homeostasis. Loss of this function is directly linked to progression of diabetes. The loss of …

The impact of the diet in adult C57BI/6J mice pancreas function with age

ATB Maduro - 2021 - estudogeral.uc.pt
Ageing is a multi-factorial biological process that generates progressive deterioration across
multiple organs, resulting in tissue dysfunction. Obesity is a metabolic condition associated …