Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

The composition of the lung microbiome is increasingly well characterised, with changes in
microbial diversity or abundance observed in association with several chronic respiratory …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Workers in the mining and construction industries are at increased risk of respiratory and
other diseases as a result of being exposed to harmful levels of airborne particulate matter …

Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of
the bronchi and is characterised by chronic infection and associated inflammation. The …

ABSTRACT COPD is a major global concern, increasingly so in the context of ageing
populations. The role of infections in disease pathogenesis and progression is known to be …

The prevalence of chronic immune and metabolic disorders is increasing rapidly. In
particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive …

Neisseria species are frequently identified in the bronchiectasis microbiome, but they are
regarded as respiratory commensals. Using a combination of human cohorts, next …

The exact pathogenesis of chronic obstructive pulmonary disease (COPD) remains largely
unknown. While current management strategies are effective at stabilizing the disease or …

A rich body of literature indicates that environmental factors interact with the human
microbiome and influence its composition and functions contributing to the pathogenesis of …