Therapeutic DNAzymes: from structure design to clinical applications
Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their
prosperous gene regulation capability. The efficacy of DNAzymes against many types of …
prosperous gene regulation capability. The efficacy of DNAzymes against many types of …
Nano-labeled materials as detection tags for signal amplification in immunochromatographic assay
The immunochromatographic assay (ICA) was widely used in rapid detection in many fields
due to its advantages such as economy, simplicity, sensitivity, and specificity all the time …
due to its advantages such as economy, simplicity, sensitivity, and specificity all the time …
An autocatalytic multicomponent DNAzyme nanomachine for tumor-specific photothermal therapy sensitization in pancreatic cancer
Multicomponent deoxyribozymes (MNAzymes) have great potential in gene therapy, but
their ability to recognize disease tissue and further achieve synergistic gene regulation has …
their ability to recognize disease tissue and further achieve synergistic gene regulation has …
An immunochromatographic sensor for ultrasensitive and direct detection of histamine in fish
L Zeng, X Xu, L Guo, Z Wang, H Ding, S Song… - Journal of hazardous …, 2021 - Elsevier
To ensure food quality and prevent histamine (HA) toxicity, a rapid and direct method of
detecting HA is required. In this work, we prepared a monoclonal antibody (mAb) against HA …
detecting HA is required. In this work, we prepared a monoclonal antibody (mAb) against HA …
Hollow mesoporous manganese oxides: application in cancer diagnosis and therapy
W Xu, X Qing, S Liu, D Yang, X Dong, Y Zhang - Small, 2022 - Wiley Online Library
The precision, minimal invasiveness, and integration of diagnosis and treatment are critical
factors for tumor treatment at the present. Although nanomedicine has shown the potential in …
factors for tumor treatment at the present. Although nanomedicine has shown the potential in …
Colorimetric biosensing assays based on gold nanoparticles functionalized/combined with non-antibody recognition elements
Biosensing assays involving antibody-antigen interactions have been widely applied in
diagnostics and healthcare in virtue of their superior selectivity and sensitivity. However …
diagnostics and healthcare in virtue of their superior selectivity and sensitivity. However …
Engineered protein nanodrug as an emerging therapeutic tool
Functional proteins are the most versatile macromolecules. They can be obtained by
extraction from natural sources or by genetic engineering technologies. The outstanding …
extraction from natural sources or by genetic engineering technologies. The outstanding …
An integrated dual-layer microfluidic platform for multiple respiratory viruses screening
H Wang, J Xu, S Li, X Wang, G Liu, S Yang, F Zhao… - Analytica Chimica …, 2023 - Elsevier
Currently, the coronavirus disease 2019 (COVID-19) caused by the outbreak of a novel
coronavirus (SARS-CoV-2) is spreading rapidly worldwide. Due to the high incidence of …
coronavirus (SARS-CoV-2) is spreading rapidly worldwide. Due to the high incidence of …
Point-of-care COVID-19 testing: colorimetric diagnosis using rapid and ultra-sensitive ramified rolling circle amplification
MH Choi, GSR Kumara, J Lee, YJ Seo - Analytical and Bioanalytical …, 2022 - Springer
In this paper, we report a molecular diagnostic system—combining a colorimetric probe
(RHthio-CuSO 4) for pyrophosphate sensing and isothermal gene amplification (ramified …
(RHthio-CuSO 4) for pyrophosphate sensing and isothermal gene amplification (ramified …
Gold nanoparticle smartphone platform for diagnosing urinary tract infections
K Zagorovsky, MT Fernández-Argüelles… - ACS Nanoscience …, 2022 - ACS Publications
Current urinary tract infection (UTI) diagnostic methods are slow or provide limited
information, resulting in prescribing antibiotic therapy before bacterial pathogen …
information, resulting in prescribing antibiotic therapy before bacterial pathogen …