Sex‐specific and hormone‐related differences in vascular remodelling in atherosclerosis

A Yerly, EPC van der Vorst… - European Journal of …, 2023 - Wiley Online Library
Atherosclerosis, a lipid‐driven inflammatory disease, is the main underlying cause of
cardiovascular diseases (CVDs) both in men and women. Sex‐related dimorphisms …

Immune cell activation in obesity and cardiovascular disease

JN Garcia, CN Wanjalla, M Mashayekhi… - Current Hypertension …, 2022 - Springer
Abstract Purpose of Review In this review, we focus on immune cell activation in obesity and
cardiovascular disease, highlighting specific immune cell microenvironments present in …

Peripheral immune cell composition is altered in women before and after a hypertension diagnosis

JK Kresovich, Z Xu, KM O'Brien, CG Parks… - …, 2023 - Am Heart Assoc
Background: The development and consequences of hypertension involve multiple
biological systems that may include changes in immune profiles. Whether hypertension is …

A comparison of the disease occurrence of cerebrovascular diseases, diabetes mellitus, hypertensive diseases, and ischaemic heart diseases among hospitalized …

P Suanrueang - Scientific Reports, 2024 - nature.com
This observational research analyzed public hospital data from the Thailand Ministry of
Public Health website to investigate gender differences in four categories of non …

Endothelial mechanical stretch regulates the immunological synapse interface of renal endothelial cells in a sex-dependent manner

CA Colvert, KP Hawkins… - American Journal …, 2023 - journals.physiology.org
Increased mechanical endothelial cell stretch contributes to the development of numerous
cardiovascular and renal pathologies. Recent studies have shone a light on the importance …

Renal TLR-7/TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension

S Chaudhari, BM D'Souza… - American Journal …, 2022 - journals.physiology.org
Hypertension is prevalent in patients with systemic lupus erythematosus (SLE). The goal of
the current study is to track the pathogenesis of hypertension and renal injury in SLE, identify …

The antihypertensive and diuretic effect of crude root extract and saponins from Solanum sisymbriifolium Lam., in L-NAME-induced hypertension in rats

DA Ibarrola, W Arrua, JE Gonzalez… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Solanum sisymbriifolium Lam., is used in
Paraguayan folk medicine claiming antihypertensive and diuretic properties. Aim of the …

Primary Mouse Aortic Smooth Muscle Cells Exhibit Region-and Sex-Dependent Biological Responses In Vitro

N Karbasion, Y Xu, JC Snider… - Journal of …, 2024 - asmedigitalcollection.asme.org
Despite advancements in elucidating biological mechanisms of cardiovascular remodeling,
cardiovascular disease (CVD) remains the leading cause of death worldwide. When …

Sex differences in vascular function

TJ Costa, RC Tostes - Cardiovascular Neuroendocrinology, 2023 - Springer
Sex is an important biological variable that impacts several organism functions at the
genetic, molecular, and cellular levels. Sex differences are observed in all components of …

Screening and validation of double allele-specific binding F-primers for the measurement of antihypertensive pharmacogenomics

Y Ping, S Quanlin, H Yue, Z Jing, L Wenjun - Frontiers in Medicine, 2023 - frontiersin.org
Objective Previous studies have proposed that genetic polymorphisms of CYP2D6* 10,
ADRB1, NPPA, CYP3A5* 3, ACE, CYP2C9* 3, and AGTR1 are involved in antihypertensive …