Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types

N Su, C Villicana, F Yang - Biomaterials, 2022 - Elsevier
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Modulation of immune-inflammatory responses through surface modifications of biomaterials to promote bone healing and regeneration

F Batool, H Özçelik, C Stutz… - Journal of Tissue …, 2021 - journals.sagepub.com
Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds

JM Sadowska, MP Ginebra - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

Resolution of inflammation in bone regeneration: From understandings to therapeutic applications

H Newman, YV Shih, S Varghese - Biomaterials, 2021 - Elsevier
Impaired bone healing occurs in 5–10% of cases following injury, leading to a significant
economic and clinical impact. While an inflammatory response upon injury is necessary to …

Pore size of 3D-printed polycaprolactone/polyethylene glycol/hydroxyapatite scaffolds affects bone regeneration by modulating macrophage polarization and the …

W Li, F Dai, S Zhang, F Xu, Z Xu, S Liao… - … Applied Materials & …, 2022 - ACS Publications
3D-printed porous bioactive ceramic scaffolds have been widely used in bone defect repair.
However, material implantation is often accompanied by a foreign body response (FBR) …

[HTML][HTML] Calcium phosphate-based materials regulate osteoclast-mediated osseointegration

X Wang, Y Yu, L Ji, Z Geng, J Wang, C Liu - Bioactive Materials, 2021 - Elsevier
Calcium phosphate-based materials (CaP) have been widely used as bone graft substitutes
with a decent osseointegration. However, the mechanism whereby cells function and repair …

[HTML][HTML] Early osteoimmunomodulation by mucin hydrogels augments the healing and revascularization of rat critical-size calvarial bone defects

S Chen, H Wang, D Liu, J Bai, HJ Haugen, B Li, H Yan - Bioactive materials, 2023 - Elsevier
The design principle of osteogenic bone grafts has shifted from immunological inertness to
limiting foreign body response to combined osteoimmunomodulatory activity to promote high …

[HTML][HTML] Additively manufactured Bi-functionalized bioceramics for reconstruction of bone tumor defects

R Belluomo, A Khodaei, SA Yavari - Acta Biomaterialia, 2023 - Elsevier
Bone tissue exhibits critical factors for metastatic cancer cells and represents an extremely
pleasant spot for further growth of tumors. The number of metastatic bone lesions and …

Allogenic bone graft in dentistry: a review of current trends and developments

M Ciszyński, S Dominiak, M Dominiak… - International Journal of …, 2023 - mdpi.com
In an effort to prepare non-autologous bone graft or biomaterial that would possess
characteristics comparable to autologous bone, many different allogenic bone derivatives …