For many decades, Escherichia coli was the main model organism for the study of bacterial
membrane lipids. The results obtained served as a blueprint for membrane lipid …

The evolution of metabolic pathways is a major force behind natural selection. In the
spotlight of such process lies the structural evolution of the enzymatic machinery responsible …

Inositol lipids are ubiquitous in eukaryotes and have finely tuned roles in cellular signalling
and membrane homoeostasis. In Bacteria, however, inositol lipid production is relatively …

Climate change and extreme climatic events, such as marine heatwaves (MHWs), are
threatening seagrass ecosystems. Metabolomics can be used to gain insight into early …

Bacteria have acquired sophisticated mechanisms for assembling and disassembling
polysaccharides of different chemistry. α-d-Glucose homopolysaccharides, so-called α …

Phosphatidylinositol is critical for intracellular signalling and anchoring of carbohydrates and
proteins to outer cellular membranes. The defining step in phosphatidylinositol biosynthesis …

The contribution of metabolism to heat stress may play a significant role in defining
robustness and recovery of systems; either by providing the energy and metabolites …

The CDP-alcohol phosphotransferase (CDP-AP) family of integral membrane enzymes
catalyses the transfer of a substituted phosphate group from a CDP-linked donor to an …

Phospholipids have major roles in the structure and function of all cell membranes. Most
integral membrane proteins from the large CDP-alcohol phosphatidyltransferase family are …

ADP-glucose pyrophosphorylase (AGPase) catalyzes the rate-limiting step of bacterial
glycogen and plant starch biosynthesis, the most common carbon storage polysaccharides …