Toxicity testing in the 21st century: progress in the past decade and future perspectives

D Krewski, ME Andersen, MG Tyshenko… - Archives of …, 2020 - Springer
Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …

The pockets guide to HLA class I molecules

AT Nguyen, C Szeto, S Gras - Biochemical Society Transactions, 2021 - portlandpress.com
Human leukocyte antigens (HLA) are cell-surface proteins that present peptides to T cells.
These peptides are bound within the peptide binding cleft of HLA, and together as a …

Predicting HLA class II antigen presentation through integrated deep learning

B Chen, MS Khodadoust, N Olsson, LE Wagar… - Nature …, 2019 - nature.com
Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II
molecules would be valuable for vaccine development and cancer immunotherapies …

AnOxPePred: using deep learning for the prediction of antioxidative properties of peptides

TH Olsen, B Yesiltas, FI Marin, M Pertseva… - Scientific reports, 2020 - nature.com
Dietary antioxidants are an important preservative in food and have been suggested to help
in disease prevention. With consumer demands for less synthetic and safer additives in food …

Review of machine learning and deep learning models for toxicity prediction

W Guo, J Liu, F Dong, M Song, Z Li… - Experimental …, 2023 - journals.sagepub.com
The ever-increasing number of chemicals has raised public concerns due to their adverse
effects on human health and the environment. To protect public health and the environment …

Machine learning models for predicting cytotoxicity of nanomaterials

Z Ji, W Guo, EL Wood, J Liu, S Sakkiah… - Chemical Research …, 2022 - ACS Publications
The wide application of nanomaterials in consumer and medical products has raised
concerns about their potential adverse effects on human health. Thus, more and more …

Deep learning models for predicting gas adsorption capacity of nanomaterials

W Guo, J Liu, F Dong, R Chen, J Das, W Ge, X Xu… - Nanomaterials, 2022 - mdpi.com
Metal–organic frameworks (MOFs), a class of porous nanomaterials, have been widely used
in gas adsorption-based applications due to their high porosities and chemical tunability. To …

Machine learning in quantitative protein–peptide affinity prediction: implications for therapeutic peptide design

Z Li, Q Miao, F Yan, Y Meng, P Zhou - Current drug metabolism, 2019 - benthamdirect.com
Background: Protein–peptide recognition plays an essential role in the orchestration and
regulation of cell signaling networks, which is estimated to be responsible for up to 40% of …

Machine learning and deep learning for brain tumor MRI image segmentation

MKH Khan, W Guo, J Liu, F Dong, Z Li… - Experimental …, 2023 - journals.sagepub.com
Brain tumors are often fatal. Therefore, accurate brain tumor image segmentation is critical
for the diagnosis, treatment, and monitoring of patients with these tumors. Magnetic …

Genome sequencing of the sweetpotato whitefly Bemisia tabaci MED/Q

W Xie, C Chen, Z Yang, L Guo, X Yang, D Wang… - …, 2017 - academic.oup.com
The sweetpotato whitefly Bemisia tabaci is a highly destructive agricultural and ornamental
crop pest. It damages host plants through both phloem feeding and vectoring plant …