The purpose of the lens is to project a sharply focused, undistorted image of the visual
surround onto the neural retina. The first pre-requisite, therefore, is that the tissue should be …

The optical properties of the ocular lens are important to overall vision quality. As a
transparent biological tissue, the lens contributes to the overall and dynamic focussing …

Background Oesophageal cancer is one of the most deadly forms of cancer worldwide. Long
non-coding RNAs (lncRNAs) are often found to have important regulatory roles. Objective To …

Fatty change (steatosis) is the most frequent liver pathology in western countries and is
caused by a broad range of disorders such as alcohol abuse and metabolic syndrome. The …

Among sarcomeric muscles the cardiac muscle cells are unique by, inter alia, a systemic
and extended cell–cell contact structure, the intercalated disk (ID), comprising frequent and …

Desmosomes are prominent adhesion sites that are tightly associated with the cytoplasmic
intermediate filament cytoskeleton providing mechanical stability in epithelia and also in …

In the human eye, a transparent cornea and lens combine to form the" refracton" to focus
images on the retina. This requires the refracton to have a high refractive index" n," mediated …

Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate
cells, including those of the lens of the eye. IFs help integrate individual cells into their …

We review the putative functions and malfunctions of proteins encoded by genes mutated in
Charcot-Marie-Tooth disease (CMT; inherited motor and sensory neuropathies) in normal …

Tropomodulins are a family of four proteins (Tmods 1–4) that cap the pointed ends of actin
filaments in actin cytoskeletal structures in a developmentally regulated and tissue‐specific …