Molecular underpinnings of synaptic vesicle pool heterogeneity
DC Crawford, ET Kavalali - Traffic, 2015 - Wiley Online Library
Neuronal communication relies on chemical synaptic transmission for information transfer
and processing. Chemical neurotransmission is initiated by synaptic vesicle fusion with the …
and processing. Chemical neurotransmission is initiated by synaptic vesicle fusion with the …
SNARE modulators and SNARE mimetic peptides
M Khvotchev, M Soloviev - Biomolecules, 2022 - mdpi.com
The soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor
(SNARE) proteins play a central role in most forms of intracellular membrane trafficking, a …
(SNARE) proteins play a central role in most forms of intracellular membrane trafficking, a …
Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity
T Fujiwara, T Mishima, T Kofuji, T Chiba… - Journal of …, 2006 - Soc Neuroscience
The protein HPC-1/syntaxin 1A is abundantly expressed in neurons and localized in the
neuronal plasma membrane. It forms a complex with SNAP-25 (25 kDa synaptosomal …
neuronal plasma membrane. It forms a complex with SNAP-25 (25 kDa synaptosomal …
Syntaxin 1B, but not syntaxin 1A, is necessary for the regulation of synaptic vesicle exocytosis and of the readily releasable pool at central synapses
T Mishima, T Fujiwara, M Sanada, T Kofuji… - PloS one, 2014 - journals.plos.org
Two syntaxin 1 (STX1) isoforms, HPC-1/STX1A and STX1B, are coexpressed in neurons
and function as neuronal target membrane (t)-SNAREs. However, little is known about their …
and function as neuronal target membrane (t)-SNAREs. However, little is known about their …
HPC‐1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival
T Kofuji, T Fujiwara, M Sanada… - Journal of …, 2014 - Wiley Online Library
Two types of syntaxin 1 isoforms, HPC‐1/syntaxin 1A (STX 1A) and syntaxin 1B (STX 1B),
are thought to have similar functions in exocytosis of synaptic vesicles. STX 1A−/− mice …
are thought to have similar functions in exocytosis of synaptic vesicles. STX 1A−/− mice …
Syntaxin 3B is essential for the exocytosis of synaptic vesicles in ribbon synapses of the retina
L Curtis, P Datta, X Liu, N Bogdanova, R Heidelberger… - Neuroscience, 2010 - Elsevier
Ribbon synapses of the vertebrate retina are specialized synapses that release
neurotransmitter by synaptic vesicle exocytosis in a manner that is proportional to the level …
neurotransmitter by synaptic vesicle exocytosis in a manner that is proportional to the level …
Syntaxin 1 is required for DCC/Netrin‐1‐dependent chemoattraction of migrating neurons from the lower rhombic lip
T Cotrufo, RM Andrés, O Ros… - European Journal of …, 2012 - Wiley Online Library
Directed cell migration and axonal guidance are essential steps in neural development that
share many molecular mechanisms. The guidance of developing axons and migrating …
share many molecular mechanisms. The guidance of developing axons and migrating …
Impairment of catecholamine systems during induction of long-term potentiation at hippocampal CA1 synapses in HPC-1/syntaxin 1A knock-out mice
T Mishima, T Fujiwara, T Kofuji… - Journal of …, 2012 - Soc Neuroscience
The membrane protein HPC-1/syntaxin 1A is believed to play a key role in synaptic vesicle
exocytosis, and it was recently suggested to be required for synaptic plasticity. Despite …
exocytosis, and it was recently suggested to be required for synaptic plasticity. Despite …
Fast, Ca2+-dependent exocytosis at nerve terminals: Shortcomings of SNARE-based models
SD Meriney, JA Umbach, CB Gundersen - Progress in neurobiology, 2014 - Elsevier
Investigations over the last two decades have made major inroads in clarifying the cellular
and molecular events that underlie the fast, synchronous release of neurotransmitter at …
and molecular events that underlie the fast, synchronous release of neurotransmitter at …
ER and Golgi stresses increase ER–Golgi SNARE Syntaxin5: Implications for organelle stress and βAPP processing
K Suga, A Saito, T Mishima, K Akagawa - Neuroscience Letters, 2015 - Elsevier
Unresolved endoplasmic reticulum (ER) stress causes neuronal death and has been
implicated in neurodegenerative conditions such as Alzheimer's disease (AD). However, the …
implicated in neurodegenerative conditions such as Alzheimer's disease (AD). However, the …