People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …

Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …

Insomnia and obstructive sleep apnea (OSA) commonly co-occur. Approximately 30–50% of
patients with OSA report clinically significant insomnia symptoms, and 30–40% of patients …

OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …

Historically, brief awakenings from sleep (cortical arousals) have been assumed to be vitally
important in restoring airflow and blood-gas disturbances at the end of obstructive sleep …

Recent insights into sleep apnoea pathogenesis reveal that a low respiratory arousal
threshold (awaken easily) is important for many patients. As most patients experience stable …

Abstract Study Objectives Precision medicine for obstructive sleep apnea (OSA) requires
noninvasive estimates of each patient's pathophysiological “traits.” Here, we provide the first …

The most striking feature of obstructive respiratory events is that they are at their most severe
and frequent in the supine sleeping position: indeed, more than half of all obstructive sleep …

There is not a clinically available technique for measuring the physiological traits causing
obstructive sleep apnea (OSA). Therefore, it is often difficult to determine why an individual …

We previously published a method for measuring several physiological traits causing
obstructive sleep apnea (OSA). The method, however, had a relatively low success rate …