Nature has achieved materials with properties and mechanisms that go far beyond the
current know-how of the engineering-materials industry. The remarkable efficiency of …

The collagen network is altered in fibrotic diseases associated with extracellular matrix
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …

Bioprinting is an emergent technology that has already demonstrated the capacity to create
complex and/or vascularized multicellular structures with defined and organized …

Optical contrasts in microscopy are sensitive to light polarization, whose interaction with
molecular dipoles provides an important lever for probing molecular orientation. Polarization …

The advancement of non-invasive quantitative optical diagnosis techniques such as
polarization-sensitive second harmonic generation microscopy (PSHG) for diseases such as …

Liver fibrosis is assessed mainly by conventional staining or second harmonic generation
(SHG) microscopy, which can only provide collagen content in fibrotic area. We propose to …

Second harmonic generation (SHG) microscopy is a commonly used technique to study the
organization of collagen within tissues. However, individual collagen fibrils, which have …

Nonlinear optical imaging techniques have been widely used to reveal biological structures
for accurate diagnosis at the cellular as well as the tissue level. In the present study …

Multimode fiber-based endoscopes have recently emerged as a tool for minimally invasive
endoscopy in tissue, at depths well beyond the reach of multiphoton imaging. Here, we …

Second harmonic generation (SHG) microscopy is acknowledged as an established
imaging technique capable to provide information on the collagen architecture in tissues that …