Overcoming cancer therapeutic bottleneck by drug repurposing

Z Zhang, L Zhou, N Xie, EC Nice, T Zhang… - Signal transduction and …, 2020 - nature.com
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Effect of Low-dose and Standard-dose Aspirin on PGE2 Biosynthesis Among Individuals with Colorectal Adenomas: A Randomized Clinical Trial

DA Drew, MM Schuck, MV Magicheva-Gupta… - Cancer Prevention …, 2020 - AACR
Low-dose aspirin is recommended by the US Preventive Services Task Force for primary
prevention of colorectal cancer in certain individuals. However, broader implementation will …

Urinary pge-m in men with prostate cancer

M Kiely, GL Milne, TZ Minas, TH Dorsey, W Tang… - Cancers, 2021 - mdpi.com
Simple Summary Elevated levels of urinary prostaglandin E metabolite (PGE-M), a marker of
inflammation, have previously been associated with cancer incidence and metastasis …

Association of urinary prostaglandin E2 metabolite and mortality among adults

W Wen, G Yang, Q Cai, XO Shu, W Zheng - Scientific Reports, 2022 - nature.com
Prostaglandins play a critical role in inflammatory response. To investigate the association of
urinary PGE-M, a stable end-product of prostaglandin E2 (PGE2) with overall and cause …

[PDF][PDF] Urinary PGE-M in Men with Prostate Cancer. Cancers 2021, 13, 0

M Kiely, GL Milne, TZ Minas, TH Dorsey, W Tang… - 2021 - researchgate.net
Urinary PGE-M is a stable metabolite of prostaglandin E2 (PGE2). PGE2 is a product of the
inflammatory COX signaling pathway and has been associated with cancer incidence and …