Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …
Omics-based biomarkers discovery for Alzheimer's disease
Q Aerqin, ZT Wang, KM Wu, XY He, Q Dong… - Cellular and Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorders presenting with
the pathological hallmarks of amyloid plaques and tau tangles. Over the past few years …
the pathological hallmarks of amyloid plaques and tau tangles. Over the past few years …
Inflammation and the pathological progression of Alzheimer's disease are associated with low circulating choline levels
Deficiency of dietary choline, an essential nutrient, is observed worldwide, with~ 90% of
Americans being deficient. Previous work highlights a relationship between decreased …
Americans being deficient. Previous work highlights a relationship between decreased …
Gut microbiota-driven metabolic alterations reveal gut–brain communication in Alzheimer's disease model mice
The gut microbiota (GM) and its metabolites affect the host nervous system and are involved
in the pathogeneses of various neurological diseases. However, the specific GM alterations …
in the pathogeneses of various neurological diseases. However, the specific GM alterations …
Curcumin hybrid molecules for the treatment of Alzheimer's disease: Structure and pharmacological activities
WB Zang, HL Wei, WW Zhang, W Ma, J Li… - European Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly. Contemporary treatments can only relieve symptoms but fail to delay disease …
elderly. Contemporary treatments can only relieve symptoms but fail to delay disease …
Metabolomic signatures of autism spectrum disorder
Autism Spectrum Disorder (ASD) is associated with many variations in metabolism, but the
ex-act correlates of these metabolic disturbances with behavior and development and their …
ex-act correlates of these metabolic disturbances with behavior and development and their …
Exploratory analysis of one versus two-day intermittent fasting protocols on the gut microbiome and plasma metabolome in adults with overweight/obesity
Nutritional interventions are a promising therapeutic option for addressing obesity and
cardiometabolic dysfunction. One such option, intermittent fasting (IF), has emerged as a …
cardiometabolic dysfunction. One such option, intermittent fasting (IF), has emerged as a …
Association of food insecurity on gut microbiome and metabolome profiles in a diverse college-based sample
Voluntary caloric restriction (eg, eating disorders) often results in alterations in the gut
microbiota composition and function. However, these findings may not translate to food …
microbiota composition and function. However, these findings may not translate to food …
Central nervous system metabolism in autism, epilepsy and developmental delays: a cerebrospinal fluid analysis
D Brister, BA Werner, G Gideon, PJ McCarty, A Lane… - Metabolites, 2022 - mdpi.com
Neurodevelopmental disorders are associated with metabolic pathway imbalances;
however, most metabolic measurements are made peripherally, leaving central metabolic …
however, most metabolic measurements are made peripherally, leaving central metabolic …
Daily vinegar ingestion improves depression scores and alters the metabolome in healthy adults: a randomized controlled trial
Daily vinegar ingestion has been linked to improved glycemic control, but recent data
suggest a separate unexplored role for vinegar in mental health. Utilizing a placebo …
suggest a separate unexplored role for vinegar in mental health. Utilizing a placebo …