Harnessing genomic information for livestock improvement

M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes

P Kalds, S Zhou, Y Gao, B Cai, S Huang… - Genetics Selection …, 2022 - Springer
Background After domestication, the evolution of phenotypically-varied sheep breeds has
generated rich biodiversity. This wide phenotypic variation arises as a result of hidden …

Signature selection analysis reveals candidate genes associated with production traits in Iranian sheep breeds

L Mohamadipoor Saadatabadi… - BMC veterinary …, 2021 - Springer
Background Sheep were among the first animals to be domesticated. They are raised all
over the world and produce a major scale of animal-based protein for human consumption …

Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

I Aguilar, A Legarra, F Cardoso, Y Masuda… - Genetics Selection …, 2019 - Springer
Background Single-step genomic best linear unbiased prediction (SSGBLUP) is a
comprehensive method for genomic prediction. Point estimates of marker effects from …

Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds

M Naval-Sanchez, Q Nguyen, S McWilliam… - Nature …, 2018 - nature.com
Domestication fundamentally reshaped animal morphology, physiology and behaviour,
offering the opportunity to investigate the molecular processes driving evolutionary change …

Revealing the selection history of adaptive loci using genome-wide scans for selection: an example from domestic sheep

CM Rochus, F Tortereau, F Plisson-Petit, G Restoux… - BMC genomics, 2018 - Springer
Background One of the approaches to detect genetics variants affecting fitness traits is to
identify their surrounding genomic signatures of past selection. With established methods for …

Genomic application in sheep and goat breeding

R Rupp, S Mucha, H Larroque, J McEwan… - Animal …, 2016 - pure.sruc.ac.uk
Genomic studies in small ruminants were first possible in 2009 with the development of the
50K ovine SNP chip.• Genomic evaluation has now been implemented in sheep in New …

Identification of selection signatures in Iranian dromedary and Bactrian camels using whole genome sequencing data

R Khalkhali-Evrigh, N Hedayat, L Ming, Jirimutu - Scientific reports, 2022 - nature.com
Abstract The Old World camels play an important role as one of the main food sources in
large parts of Asia and Africa. Natural selection combined with artificial selection by human …

Role of the JAK-STAT pathway in bovine mastitis and milk production

MZ Khan, A Khan, J Xiao, Y Ma, J Ma, J Gao, Z Cao - Animals, 2020 - mdpi.com
Simple Summary The cytokine-activated Janus kinase (JAK)—signal transducer and
activator of transcription (STAT) pathway has an important role in the regulation of immunity …

Trends towards revealing the genetic architecture of sheep tail patterning: Promising genes and investigatory pathways

P Kalds, Q Luo, K Sun, S Zhou, Y Chen… - Animal …, 2021 - Wiley Online Library
Different sheep breeds have evolved after initial domestication, generating various tail
phenotypic patterns. The phenotypic diversity of sheep tail patterns offers ideal materials for …