Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Nanobiomaterial-based vaccination immunotherapy of cancer

F Chen, Y Wang, J Gao, M Saeed, T Li, W Wang, H Yu - Biomaterials, 2021 - Elsevier
Cancer immunotherapies including cancer vaccines, immune checkpoint blockade or
chimeric antigen receptor T cells have been exploited as the attractive treatment modalities …

Nano-, micro-, and macroscale drug delivery systems for cancer immunotherapy

P Huang, X Wang, X Liang, J Yang, C Zhang, D Kong… - Acta biomaterialia, 2019 - Elsevier
Immunotherapy is moving to the frontier of cancer treatment. Drug delivery systems (DDSs)
have greatly advanced the development of cancer immunotherapeutic regimen and …

Delivery strategies of cancer immunotherapy: recent advances and future perspectives

Z Zhao, L Zheng, W Chen, W Weng, J Song… - Journal of hematology & …, 2019 - Springer
Immunotherapy has become an emerging strategy for the treatment of cancer.
Immunotherapeutic drugs have been increasing for clinical treatment. Despite significant …

Chemical conjugation strategies for the development of protein-based subunit nanovaccines

L Lu, VT Duong, AO Shalash, M Skwarczynski, I Toth - Vaccines, 2021 - mdpi.com
The production of subunit nanovaccines relies heavily on the development of a vaccine
delivery system that is safe and efficient at delivering antigens to the target site …

Enhancing immunity with nanomedicine: employing nanoparticles to harness the immune system

CT Perciani, LY Liu, L Wood, SA MacParland - ACS nano, 2020 - ACS Publications
The failure of immune responses to vaccines and dysfunctional immune responses to viral
infection, tumor development, or neoantigens lead to chronic viral infection, tumor …

[HTML][HTML] The role of vaccines in combating antimicrobial resistance (AMR) bacteria

S Alghamdi - Saudi Journal of Biological Sciences, 2021 - Elsevier
Most pathogens have developed an intrinsic capacity to thrive by developing resistance to
antimicrobial compounds utilized in treatment. Antimicrobial resistance arises when …

Toll-like receptor agonist conjugation: a chemical perspective

BJ Ignacio, TJ Albin, AP Esser-Kahn… - Bioconjugate …, 2018 - ACS Publications
Toll-like receptors (TLRs) are vital elements of the mammalian immune system that function
by recognizing pathogen-associated molecular patterns (PAMPs), bridging innate and …

Advances in vaccine development for Chlamydia trachomatis

TB Poston - Pathogens and Disease, 2024 - academic.oup.com
Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally.
Antibiotic treatment is highly effective, but infection is often asymptomatic resulting in most …

RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern

SH Zhou, RY Zhang, HW Zhang, YL Liu… - Chemical …, 2022 - pubs.rsc.org
The coronavirus 2019 (COVID-19) pandemic is causing serious impacts in the world, and
safe and effective vaccines and medicines are the best methods to combat the disease. The …