Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …

Lycopene is a compound of colored origin that shows strong antioxidant activity. The
positive effect of lycopene is the result of its pleiotropic effect. The ability to neutralize free …

Biological sex is a factor in many conditions, including aging, neurodegenerative disease,
cancer, and more. For each of these, men and women display distinct differences in disease …

Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective
agents in Parkinson's disease (PD). However, epidemiological evidence on the association …

The ability of the body to maintain homeostasis requires constant communication between
the brain and peripheral tissues. Different organs produce signals, often in the form of …

The aging of the global population has increased the prevalence of neurodegenerative
conditions. Bacopa monnieri (BM), an herb with active compounds, such as bacosides A …

Background Sex difference in the association between ambient air pollution and cognitive
aging remained unclear. This current study aimed to assess the impacts of long-term …

In swine production, stress is a common encounter that leads to serious bacterial infection
and adverse effects on growth performance. Though antibiotics have been frequently used …

Background Valosin-containing protein (VCP) disease, caused by mutations in the VCP
gene, results in myopathy, Paget's disease of bone (PBD) and frontotemporal dementia …