Microphysiological systems (MPS), also known as Organ (s)-on-Chip (OoC), are in vitro cell
culture platforms that reproduce the function of cells/tissues/organs in a microenvironment …

Morbidity and mortality rates associated with atherosclerosis-related diseases are
increasing. Therefore, developing new research models is important in furthering our …

The applicability of a gas-permeable, thermoplastic material polymethylpentene (PMP) was
investigated, experimentally and analytically, for organ-on-a-chip (OoC) and long-term on-a …

With the rapid development and commercial interest in the organ-on-a-chip (OoC) field,
there is a need for materials addressing key experimental demands and enabling both …

Spermatogenesis is one of the most complex processes of cell differentiation and its failure
is a major cause of male infertility. Therefore, a proper model that recapitulates …

Microphysiological systems (MPS) are gaining global attention as potential game-changers
in pharmaceutical development. Since 2013, MPS suppliers from university laboratories in …

The small intestine and liver play important role in determining oral drug's fate. Both organs
are also interconnected through enterohepatic circulation, which imply there are crosstalk …

In vitro culture of primary hepatocytes for drug screening purposes remains a challenge as
cells rapidly lose their function in conventional culture conditions. Thin oxygen permeable …

Drug-induced liver injury (DILI) is a major factor underlying drug withdrawal from the market.
Therefore, it is important to predict DILI during the early phase of drug discovery. Metabolic …

Co-culture systems with culture inserts are commonly used to study cell-cell interactions
mediated by soluble factors. However, the inclusion of culture inserts reduces the air …