Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

Chagas disease is the most important protozoan infection in the Americas, and constitutes a
significant public health concern throughout the world. Development of new medications …

Chagas disease (CD), caused by Trypanosoma cruzi (T. cruzi) protozoa, is a complicated
parasitic illness with inadequate medical measures for diagnosing infection and monitoring …

Introduction American trypanosomiasis, better known as Chagas disease, is a global public
health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are …

Trypanosoma cruzi is a remarkably versatile parasite. It can parasitize almost any nucleated
cell type and naturally infects hundreds of mammal species across much of the Americas. In …

Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe form of Chagas
disease, a neglected tropical illness caused by the protozoan Trypanosoma cruzi, and the …

Chagas disease is caused by infection with the protozoan parasite, Trypanosoma cruzi. The
disease causes~ 12,000 deaths annually and is one of the world's 20 neglected tropical …

Trypanosoma cruzi, the causal agent of Chagas disease, has coexisted with humans for
thousands of years. Therefore, the parasite has developed several mechanisms of antigenic …

Chagas disease is caused by Trypanosoma cruzi, and it is an important cause of morbidity
and mortality in Latin America. There are no vaccines, and the chemotherapy available to …

Current treatment for Chagas disease is based on only two drugs: benznidazole and
nifurtimox. Compounds containing sulfur (S) in their structure have shown promising results …