Insertions and deletions constitute the second most important source of natural genomic
variation. Insertions and deletions make up to 25% of genomic variants in humans and are …

Accurate reconstruction of ancestral states is a critical evolutionary analysis when studying
ancient proteins and comparing biochemical properties between parental or extinct species …

Insertions and deletions (indels) are common molecular evolutionary events. However,
probabilistic models for indel evolution are under-developed due to their computational …

Orthologs document the evolution of genes and metabolic capacities encoded in extant and
ancient genomes. However, the similarity between orthologs decays with time, and …

The most common evolutionary events at the molecular level are single-base substitutions,
as well as insertions and deletions (indels) of short DNA segments. A large body of research …

Selective sweeps occur when a beneficial mutation spreads rapidly throughout the
population due to natural selection. Searching for selective sweeps has proved to be one of …