Advances in gap-filling genome-scale metabolic models and model-driven experiments lead to novel metabolic discoveries
S Pan, JL Reed - Current opinion in biotechnology, 2018 - Elsevier
Highlights•Gap-filling is an important tool for making model-driven metabolic
discoveries.•Recent gap-filling algorithms are more efficient and/or show superior …
discoveries.•Recent gap-filling algorithms are more efficient and/or show superior …
Organohalide respiratory chains: composition, topology and key enzymes
The utilization of halogenated organic compounds as terminal electron acceptors separates
the phylogenetically diverse organohalide-respiring bacteria from other respiratory …
the phylogenetically diverse organohalide-respiring bacteria from other respiratory …
Comparative genomics of the genus Roseburia reveals divergent biosynthetic pathways that may influence colonic competition among species
Roseburia species are important denizens of the human gut microbiome that ferment
complex polysaccharides to butyrate as a terminal fermentation product, which influences …
complex polysaccharides to butyrate as a terminal fermentation product, which influences …
Sustained bacterial N2O reduction at acidic pH
Nitrous oxide (N2O) is a climate-active gas with emissions predicted to increase due to
agricultural intensification. Microbial reduction of N2O to dinitrogen (N2) is the major …
agricultural intensification. Microbial reduction of N2O to dinitrogen (N2) is the major …
Geobacter sp. Strain IAE Dihaloeliminates 1,1,2-Trichloroethane and 1,2-Dichloroethane
Chlorinated ethanes, including 1, 2-dichloroethane (1, 2-DCA) and 1, 1, 2-trichloroethane (1,
1, 2-TCA), are widespread groundwater contaminants. Enrichment cultures XRDCA and …
1, 2-TCA), are widespread groundwater contaminants. Enrichment cultures XRDCA and …
Insights into origins and function of the unexplored majority of the reductive dehalogenase gene family as a result of genome assembly and ortholog group …
Organohalide respiring bacteria (OHRB) express reductive dehalogenases for energy
conservation and growth. Some of these enzymes catalyze the reductive dehalogenation of …
conservation and growth. Some of these enzymes catalyze the reductive dehalogenation of …
Purinyl-cobamide is a native prosthetic group of reductive dehalogenases
Cobamides such as vitamin B12 are structurally conserved, cobalt-containing tetrapyrrole
biomolecules that have essential biochemical functions in all domains of life. In …
biomolecules that have essential biochemical functions in all domains of life. In …
Vitamin B12 as a source of variability in isotope effects for chloroform biotransformation by Dehalobacter
Carbon and chlorine isotope effects for biotransformation of chloroform by different microbes
show significant variability. Reductive dehalogenases (RDase) enzymes contain different …
show significant variability. Reductive dehalogenases (RDase) enzymes contain different …
An integrative overview of genomic, transcriptomic and proteomic analyses in organohalide respiration research
D Türkowsky, N Jehmlich, G Diekert… - FEMS microbiology …, 2018 - academic.oup.com
Organohalide respiration (OHR) is a crucial process in the global halogen cycle and of
interest for bioremediation. However, investigations on OHR are hampered by the restricted …
interest for bioremediation. However, investigations on OHR are hampered by the restricted …
Sustained Dechlorination of Vinyl Chloride to Ethene in Dehalococcoides-Enriched Cultures Grown without Addition of Exogenous Vitamins and at Low pH
LA Puentes Jácome, PH Wang… - Environmental …, 2019 - ACS Publications
Trichloroethene (TCE) bioremediation has been demonstrated at field sites using microbial
cultures harboring TCE-respiring Dehalococcoides whose growth is cobalamin (vitamin …
cultures harboring TCE-respiring Dehalococcoides whose growth is cobalamin (vitamin …