Hope for patients with neuromyelitis optica spectrum disorders—from mechanisms to trials

SJ Pittock, A Zekeridou, BG Weinshenker - Nature Reviews Neurology, 2021 - nature.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis

N Borisow, M Mori, S Kuwabara, M Scheel… - Frontiers in …, 2018 - frontiersin.org
Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …

Neuromyelitis spectrum disorders

BG Weinshenker, DM Wingerchuk - Mayo Clinic Proceedings, 2017 - Elsevier
The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved
substantially since its initial description over a century ago. The discovery in 2004 of a …

Efficacy and safety of rituximab therapy in neuromyelitis optica spectrum disorders: a systematic review and meta-analysis

V Damato, A Evoli, R Iorio - JAMA neurology, 2016 - jamanetwork.com
Importance Neuromyelitis optica spectrum disorders (NMOSDs) are autoimmune
astrocytopathies characterized by predominant involvement of the optic nerves and spinal …

Comparison of the response to rituximab between myelin oligodendrocyte glycoprotein and aquaporin‐4 antibody diseases

P Durozard, A Rico, C Boutiere, A Maarouf… - Annals of …, 2020 - Wiley Online Library
Objective To compare response to rituximab (RTX) between adult patients positive for
myelin oligodendrocyte glycoprotein (MOG) and aquaporin‐4 (AQP4) antibodies. Methods …

Comparison of the efficacy of azathioprine and rituximab in neuromyelitis optica spectrum disorder: a randomized clinical trial

Z Nikoo, S Badihian, V Shaygannejad, N Asgari… - Journal of …, 2017 - Springer
Neuromyelitis optica spectrum disorder (NMOSD) often follows a relapsing course. As
disability in NMOSD is attack-related, effective treatments are needed. We aimed to compare …

Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD)–revised recommendations of the Neuromyelitis Optica Study Group …

T Kümpfel, K Giglhuber, O Aktas, I Ayzenberg… - Journal of …, 2024 - Springer
This manuscript presents practical recommendations for managing acute attacks and
implementing preventive immunotherapies for neuromyelitis optica spectrum disorders …

Evaluation of treatment response in adults with relapsing MOG-Ab-associated disease

A Cobo-Calvo, M Sepúlveda, F Rollot… - Journal of …, 2019 - Springer
Background Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) are related to
several acquired demyelinating syndromes in adults, but the therapeutic approach is …

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

JP Stellmann, M Krumbholz, T Friede… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective To analyse predictors for relapses and number of attacks under different
immunotherapies in patients with neuromyelitis optica spectrum disorder (NMOSD). Design …

Latin American consensus recommendations for management and treatment of neuromyelitis optica spectrum disorders in clinical practice

EC Contentti, JI Rojas, E Cristiano, VD Marques… - Multiple sclerosis and …, 2020 - Elsevier
Background During the last two decades, neuromyelitis optica spectrum disorder (NMOSD)
has undergone important changes, with new diagnostic markers and criteria, better …