On the mechanism of organelle degradation in the vertebrate lens

S Bassnett - Experimental eye research, 2009 - Elsevier
The programmed elimination of cytoplasmic organelles occurs during terminal differentiation
of erythrocytes, keratinocytes and lens fiber cells. In each case, the process is relatively well …

Optical coherence tomography and histology of age-related macular degeneration support mitochondria as reflectivity sources

KM Litts, Y Zhang, KB Freund, CA Curcio - Retina, 2018 - journals.lww.com
Purpose: Widespread adoption of optical coherence tomography has revolutionized the
diagnosis and management of retinal disease. If the cellular and subcellular sources of …

Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank

SYL Chua, A Warwick, T Peto, K Balaskas… - British Journal of …, 2022 - bjo.bmj.com
Aim To examine the associations of air pollution with both self-reported age-related macular
degeneration (AMD), and in vivo measures of retinal sublayer thicknesses. Methods We …

Doxorubicin-incorporated nanotherapeutic delivery system based on gelatin-coated gold nanoparticles: formulation, drug release, and multimodal imaging of cellular …

S Suarasan, M Focsan, M Potara… - … applied materials & …, 2016 - ACS Publications
In this work, we developed a new pH-and temperature-responsive nanochemotherapeutic
system based on Doxorubicin (DOX) noncovalently bound to biosynthesized gelatin-coated …

Light scattering from collagen fiber networks: micro-optical properties of normal and neoplastic stroma

D Arifler, I Pavlova, A Gillenwater, R Richards-Kortum - Biophysical journal, 2007 - cell.com
Abstract Development of epithelial precancer and cancer leads to well-documented
molecular and structural changes in the epithelium. Recently, it has been recognized that …

Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies

ZA Steelman, WJ Eldridge, JB Weintraub… - Journal of …, 2017 - Wiley Online Library
The refractive index (RI) of biological materials is a fundamental parameter for the optical
characterization of living systems. Numerous light scattering technologies are grounded in a …

[HTML][HTML] Inner segment remodeling and mitochondrial translocation in cone photoreceptors in age-related macular degeneration with outer retinal tubulation

KM Litts, JD Messinger, KB Freund… - … & visual science, 2015 - jov.arvojournals.org
Purpose.: To quantify impressions of mitochondrial translocation in degenerating cones and
to determine the nature of accumulated material in the subretinal space with apparent inner …

Index-of-refraction-dependent subcellular light scattering observed with organelle-specific dyes

JD Wilson, WJ Cottrell… - Journal of biomedical …, 2007 - spiedigitallibrary.org
Angularly resolved light scattering and wavelength-resolved darkfield scattering
spectroscopy measurements were performed on intact, control EMT6 cells and cells stained …

[HTML][HTML] Reduced electron transport chain complex I protein abundance and function in Mfn2-deficient myogenic progenitors lead to oxidative stress and mitochondria …

N Luo, F Yue, Z Jia, J Chen, Q Deng… - … : official publication of …, 2021 - ncbi.nlm.nih.gov
Mitochondrial remodeling through fusion and fission is crucial for progenitor cell
differentiation but its role in myogenesis is poorly understood. Here, we characterized the …

Apoptosis-and necrosis-induced changes in light attenuation measured by optical coherence tomography

FJ van der Meer, DJ Faber, MCG Aalders… - Lasers in medical …, 2010 - Springer
Optical coherence tomography (OCT) was used to determine optical properties of pelleted
human fibroblasts in which necrosis or apoptosis had been induced. We analysed the OCT …