Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …

There is increasing evidence that neurotrophins (NTs) are involved in processes of neuronal
plasticity besides their well-established actions in regulating the survival, differentiation, and …

The role of neurotrophic factors in the maintenance and survival of peripheral neuronal cells
has been the subject of numerous studies. Administration of exogenous neurotrophic factors …

Wallerian degeneration (WD) is the set of molecular and cellular events by which
degenerating axons and myelin are cleared after injury. Why WD is rapid and robust in the …

A recurrent observation in the development of the nervous system is the generation of
neurons followed by their large scale elimination. This phenomenon, usually referred to as …

Nerve growth factor (NGF) is a trophic agent that promotes the outgrowth of nerve fibers from
sympathetic and sensory ganglia. The neuronal differentiation stimulated by this hormone …

Although the requirement of neurotrophins for the prevention of cell death in the peripheral
nervous system is well established, their physiological involvement in nerve growth is still …

1 Peripheral inflammation is associated with the local production of neuroactive
inflammatory cytokines and growth factors. These may contribute to inflammatory pain and …

Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are molecules
which regulate the development and maintenance of specific functions in different …

The mRNAs of nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF)
exhibit a similar, though not identical, regional and cellular distribution in the rodent brain. In …