Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. AF and its
complications are responsible for important population morbidity and mortality. Presently …

MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Since their discovery 20 years ago, microRNAs have been related to posttranscriptional
regulation of gene expression in major cardiac physiological and pathological processes …

Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …

Exosomes are nanosized membrane particles that are secreted by cells that transmit
information from cell to cell. The information within exosomes prominently includes their …

Cardiac exosomes mediate cell-to-cell communication, stimulate or inhibit the activities of
target cells, and affect myocardial hypertrophy, injury and infarction, ventricular remodeling …

Extracellular vesicles (EVs) are nanoscale extracellular vesicles derived from endocytosis
that are crucial to intercellular communication. EVs possess natural biocompatibility and …

The interest in non-coding RNAs, which started more than a decade ago, has still not
weakened. A wealth of experimental and clinical studies has suggested the potential of non …

Regulation of intracellular calcium (Ca 2+) is critical in all cell types. The ryanodine receptor
(RyR), an intracellular Ca 2+ release channel located on the sarco/endoplasmic reticulum …