Biological utility of fluorinated compounds: from materials design to molecular imaging, therapeutics and environmental remediation

C Zhang, K Yan, C Fu, H Peng, CJ Hawker… - Chemical …, 2021 - ACS Publications
The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

J Lv, Y Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Fluoropolymers have unique physicochemical properties such as hydrophobicity and
lipophobicity, good chemical stability and bio-inertness, low surface energy and phase …

Application of dendrimers in anticancer diagnostics and therapy

Z Bober, D Bartusik-Aebisher, D Aebisher - Molecules, 2022 - mdpi.com
The application of dendrimeric constructs in medical diagnostics and therapeutics is
increasing. Dendrimers have attracted attention due to their compact, spherical three …

Regioselective Aromatic Perfluoro-tert-butylation Using Perfluoro-tert-butyl Phenyl Sulfone and Arynes

Z Wei, L Wen, K Zhu, Q Wang, Y Zhao… - Journal of the American …, 2022 - ACS Publications
The selective introduction of perfluoro-tert-butyl group (PFtB, the bulkier analogue of CF3
group) into arenes has long been sought after but remains a formidable task. We herein …

Nanoparticles as theranostic vehicles in experimental and clinical applications—focus on prostate and breast cancer

J Elgqvist - International journal of molecular sciences, 2017 - mdpi.com
Prostate and breast cancer are the second most and most commonly diagnosed cancer in
men and women worldwide, respectively. The American Cancer Society estimates that …

Functional polymers as metal-free magnetic resonance imaging contrast agents

C Fu, Y Yu, X Xu, Q Wang, Y Chang, C Zhang… - Progress in Polymer …, 2020 - Elsevier
Magnetic resonance imaging (MRI) is recognized as the most powerful clinical imaging
modality due to its ability to generate detailed three-dimensional anatomical images with …

PFPE-Based Polymeric 19F MRI Agents: A New Class of Contrast Agents with Outstanding Sensitivity

C Zhang, SS Moonshi, Y Han, S Puttick, H Peng… - …, 2017 - ACS Publications
19F magnetic resonance imaging (MRI) is a powerful noninvasive imaging technique with
demonstrated potential for the detection of important diseases. The major challenge in the …

19F‐Labeled Probes for Recognition‐Enabled Chromatographic 19F NMR

Z Xu, Y Zhao - The Chemical Record, 2023 - Wiley Online Library
The NMR technique is among the most powerful analytical methods for molecular structural
elucidation, process monitoring, and mechanistic investigations; however, the direct analysis …

Two decades of dendrimers as versatile MRI agents: a tale with and without metals

MT McMahon, JWM Bulte - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Dendrimers or dendritic polymers are a class of compounds with great potential for
nanomedical use. Some of their properties, including their rigidity, low polydispersity and the …

Perfluoro-tert-butanol: A cornerstone for high performance fluorine-19 magnetic resonance imaging

T Wu, A Li, K Chen, X Peng, J Zhang, M Jiang… - Chemical …, 2021 - pubs.rsc.org
As a versatile quantification and tracking technology, 19F magnetic resonance imaging (19F
MRI) provides quantitative “hot-spot” images without ionizing radiation, tissue depth limit …