Synovial sarcoma (SS) is a rare sarcoma driven by a translocation between SS18 and SSX
1, 2, or 4. With approximately 800 to 1,000 cases a year in the United States, it most …

Synovial sarcoma (SS) is a rare and aggressive disease that accounts for 5%-10% of all soft
tissue sarcomas. Although it can occur at any age, it typically affects younger adults and …

Reduced protein levels of SMARCB1 (also known as BAF47, INI1, SNF5) have long been
observed in synovial sarcoma. Here, we show that combined Smarcb1 genetic loss with …

Background Afamitresgene autoleucel (afami-cel) showed acceptable safety and promising
efficacy in a phase 1 trial (NCT03132922). The aim of this study was to further evaluate the …

Purpose: To investigate the metabolism of synovial sarcoma (SS) and elucidate the effect of
malic enzyme 1 absence on SS redox homeostasis. Experimental Design: ME1 expression …

Clear cell sarcoma (CCS) is a deadly malignancy affecting adolescents and young adults. It
is characterized by reciprocal translocations resulting in expression of the chimeric EWSR1 …

Background Embedding techniques for converting high-dimensional sparse data into low-
dimensional distributed representations have been gaining popularity in various fields of …

Soft tissue tumors are rare mesenchymal tumors with divergent differentiation. The diagnosis
of soft tissue tumors is challenging for pathologists owing to the diversity of tumor types and …

Sarcoma is a rare tumor type that occurs most frequently in connective tissue. Despite its
uncommon occurrence, sarcoma research has provided the means for groundbreaking …

Background Synovial sarcoma (SS) is an aggressive soft tissue tumor with limited
therapeutic options in advanced stage. SS18-SSX fusion oncogenes, which are the …