The chick embryo chorioallantoic membrane (CAM) assay

D Ribatti - Reproductive toxicology, 2017 - Elsevier
During avian development the mesodermal layers of the allantois and chorion fuse to form
the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich …

The CAM model—Q&A with experts

D Fischer, G Fluegen, P Garcia… - Cancers, 2022 - mdpi.com
Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …

Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells

E Garreta, P Prado, C Tarantino, R Oria, L Fanlo… - Nature materials, 2019 - nature.com
The generation of organoids is one of the biggest scientific advances in regenerative
medicine. Here, by lengthening the time that human pluripotent stem cells (hPSCs) were …

[HTML][HTML] The chick chorioallantoic membrane (CAM) as a versatile patient-derived xenograft (PDX) platform for precision medicine and preclinical research

LC DeBord, RR Pathak, M Villaneuva… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Patient-derived xenografts (PDX) are an increasingly valuable tool in oncology, providing
biologically faithful models of many different cancer types, and potential platforms for the …

[HTML][HTML] Cellular antioxidant properties of nontoxic exopolysaccharide extracted from Lactobacillales (Weissella cibaria) isolated from Korean kimchi

S Park, K Saravanakumar, A Sathiyaseelan, SJ Park… - Lwt, 2022 - Elsevier
The present work isolated and identified five lactic acid bacteria (LAB) from Korean kimchi
and then evaluated their exopolysaccharide (EPS) production efficiency. SY003 (Weissella …

Biomolecular interaction, anti-cancer and anti-angiogenic properties of cobalt (III) Schiff base complexes

S Ambika, Y Manojkumar, S Arunachalam… - Scientific reports, 2019 - nature.com
Two cobalt (III) Schiff base complexes, trans-[Co (salen)(DA) 2](ClO4)(1) and trans-[Co
(salophen)(DA) 2](ClO4)(2)(where salen: N, N'-bis (salicylidene) ethylenediamine, salopen …

Utilisation of chick embryo chorioallantoic membrane as a model platform for imaging-navigated biomedical research

L Chen, S Wang, Y Feng, J Zhang, Y Du, J Zhang… - Cells, 2021 - mdpi.com
The fertilised chick egg and particularly its chorioallantoic membrane (CAM) have drawn
continuing interest in biomedicine and bioengineering fields, especially for research on …

Alternative animal models in predictive toxicology

MNH Khabib, Y Sivasanku, HB Lee, S Kumar, CS Kue - Toxicology, 2022 - Elsevier
Toxicity testing relies heavily on animals, especially rodents as part of the non-clinical
laboratory testing of substances. However, the use of mammalians and the number of …

Monitoring of tumor growth and vascularization with repetitive ultrasonography in the chicken chorioallantoic-membrane-assay

J Eckrich, P Kugler, CR Buhr, BP Ernst, S Mendler… - Scientific reports, 2020 - nature.com
Abstract The chorioallantoic-membrane (CAM)-assay is an established model for in vivo
tumor research. Contrary to rodent-xenograft-models, the CAM-assay does not require …

Treatment of oxidative stress-induced pain and inflammation with dexketoprofen trometamol loaded different molecular weight chitosan nanoparticles: Formulation …

AA Öztürk, HT Kıyan - Microvascular Research, 2020 - Elsevier
Angiogenesis is a fundamental process of wound healing, embryogenesis etc. but occurs in
cancer and chronic inflammation pathologically. HET-CAM assay is a useful, well …