Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development

ME Patarroyo, A Bermúdez, MA Patarroyo - Chemical reviews, 2011 - ACS Publications
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …

Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design

LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …

A co-ligand complex anchors Plasmodium falciparum merozoites to the erythrocyte invasion receptor band 3

X Li, H Chen, TH Oo, TM Daly, LW Bergman… - Journal of Biological …, 2004 - ASBMB
In Plasmodium falciparum malaria, erythrocyte invasion by circulating merozoites may occur
via two distinct pathways involving either a sialic acid-dependent or-independent …

A Duffy Binding—Like Domain Is Involved in the NKp30-Mediated Recognition of Plasmodium falciparum—Parasitized Erythrocytes by Natural Killer Cells

E Mavoungou, J Held, L Mewono… - The Journal of …, 2007 - academic.oup.com
The recent demonstration that purified natural killer (NK) cells lyse Plasmodium falciparum–
parasitized red blood cells (Pf-pRBCs) suggests that innate immunity is important in malaria …

Cellular adhesive phenomena in apicomplexan parasites of red blood cells

BM Cooke, N Mohandas, AF Cowman, RL Coppel - Veterinary parasitology, 2005 - Elsevier
The apicomplexan parasites Babesia and Plasmodium are related, yet phylogenetically
distinct haemoprotozoa that infect red blood cells and cause severe diseases of major …

Strategies for developing multi‐epitope, subunit‐based, chemically synthesized anti‐malarial vaccines

ME Patarroyo, G Cifuentes, A Bermudez… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• P. falciparum invasion of RBCs• Merozoite proteins involved in invading
erythrocytes• Erythrocyte proteins involved in merozoite invasion• The state of current …

Protective Immunity Induced by Virus-Like Particle Containing Merozoite Surface Protein 9 of Plasmodium berghei

SH Lee, HJ Kang, KB Chu, S Basak, DH Lee, EK Moon… - Vaccines, 2020 - mdpi.com
Merozoite surface protein 9 (MSP-9) from Plasmodium has shown promise as a vaccine
candidate due to its location and possible role in erythrocyte invasion. In this study, we …

Deletion of the Plasmodium falciparum Merozoite Surface Protein 7 Gene Impairs Parasite Invasion of Erythrocytes

M Kadekoppala, RA O'Donnell, M Grainger… - Eukaryotic …, 2008 - Am Soc Microbiol
Merozoite surface proteins have been implicated in the initial attachment to the host red
blood cell membrane that begins the process of invasion, an important step in the life cycle …

Identification of conserved erythrocyte binding regions in members of the Plasmodium falciparum Cys6 lipid raft-associated protein family

J García, H Curtidor, CG Pinzón, M Vanegas, A Moreno… - Vaccine, 2009 - Elsevier
Detergent-resistant lipid raft membrane-associated Pf12, Pf38 and Pf41 proteins belong to
the Cys6 family, whose members are implicated in Plasmodium falciparum invasion to …

Identifying Plasmodium falciparum merozoite surface antigen 3 (MSP3) protein peptides that bind specifically to erythrocytes and inhibit merozoite invasion

LE Rodríguez, H Curtidor, M Ocampo, J Garcia… - Protein …, 2005 - Wiley Online Library
Receptor–ligand interactions between synthetic peptides and normal human erythrocytes
were studied to determine Plasmodium falciparum merozoite surface protein‐3 (MSP‐3) …