Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Fibroepithelial lesions; The WHO spectrum

G Krings, GR Bean, YY Chen - Seminars in diagnostic pathology, 2017 - Elsevier
Fibroepithelial lesions of the breast comprise a morphologically and biologically
heterogeneous group of biphasic tumors with epithelial and stromal components that …

[HTML][HTML] Fibroepithelial lesions revisited: implications for diagnosis and management

PH Tan - Modern Pathology, 2021 - Elsevier
Fibroepithelial lesions of the breast, comprising the fibroadenoma and phyllodes tumour, are
a unique group of neoplasms that share histological characteristics but possess different …

Histopathologic, immunophenotypic, and proteomics characteristics of low-grade phyllodes tumor and fibroadenoma: more similarities than differences

L Zhang, C Yang, JD Pfeifer, RM Caprioli, AM Judd… - NPJ breast …, 2020 - nature.com
Distinguishing low-grade phyllodes tumor from fibroadenoma is practically challenging due
to their overlapping histologic features. However, the final interpretation is essential to …

[HTML][HTML] Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into …

SY Liu, NM Joseph, A Ravindranathan, BA Stohr… - Modern Pathology, 2016 - Elsevier
Malignant phyllodes tumors of the breast are poorly understood rare neoplasms with
potential for aggressive behavior. Few efficacious treatment options exist for progressed or …

[HTML][HTML] Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

CCY Ng, NDM Nasir, BN Loke, TKY Tay, AA Thike… - Modern Pathology, 2021 - Elsevier
Breast fibroepithelial lesions are biphasic tumors which comprise the common benign
fibroadenomas (FAs) and the rarer phyllodes tumors (PTs). This study analyzed 262 (42%) …

Genomic characterisation of breast fibroepithelial lesions in an international cohort

ND Md Nasir, CCY Ng, V Rajasegaran… - The Journal of …, 2019 - Wiley Online Library
Fibroepithelial lesions (FELs) are a heterogeneous group of tumours comprising
fibroadenomas (FAs) and phyllodes tumours (PTs). Here we used a 16‐gene panel that was …

Immunogenomic landscape analyses of immune molecule signature-based risk panel for patients with triple-negative breast cancer

C Liu, Y Li, X Xing, J Zhuang, J Wang, C Wang… - … Therapy-Nucleic Acids, 2022 - cell.com
Triple-negative breast cancer (TNBC) presented as high heterogeneous immunogenicity
that lacks useful clinical signatures to risk-stratify immune-benefit subtypes. We …

Genetics and genomics of breast fibroadenomas

BN Loke, NDM Nasir, AA Thike, JYH Lee… - Journal of clinical …, 2018 - jcp.bmj.com
Fibroadenomas of the breast are benign fibroepithelial tumours most frequently encountered
in women of reproductive age, although they may be diagnosed at any age. The …

MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours

DA Garcia-Dios, D Levi, V Shah, C Gillett… - British journal of …, 2018 - nature.com
Background: MED12 and TERT promoter mutations have been shown to be the most
common somatic mutations in phyllodes tumours (PTs). The aims of this study were to …