Macrophage M1/M2 polarization

C Yunna, H Mengru, W Lei, C Weidong - European journal of …, 2020 - Elsevier
Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

A review on the role of M2 macrophages in bladder cancer; pathophysiology and targeting

L Sharifi, MR Nowroozi, E Amini, MK Arami… - International …, 2019 - Elsevier
Tumor-associated macrophages (TAMs) which are often referred to as immunosuppressive
cells (M2 macrophage), constitute a subset of tumor microenvironment cells and affect tumor …

[HTML][HTML] Macrophages are recruited to hypoxic tumor areas and acquire a pro-angiogenic M2-polarized phenotype via hypoxic cancer cell derived cytokines …

C Tripathi, BN Tewari, RK Kanchan, KS Baghel… - Oncotarget, 2014 - ncbi.nlm.nih.gov
TAMs, a unique and distinct M2-skewed myeloid population of tumor stroma, exhibiting pro-
tumor functions is fast emerging as a potential target for anti-cancer immunotherapy …

The role of the hypoxia‐Nrp‐1 axis in the activation of M2‐like tumor‐associated macrophages in the tumor microenvironment of cervical cancer

XJ Chen, S Wu, RM Yan, LS Fan, L Yu… - Molecular …, 2019 - Wiley Online Library
To explore the mechanisms through which hypoxic tumor microenvironment (TME)
modulates the transition of tumor‐associated macrophages (TAMs). The migration ability of …

Promises and challenges of predictive blood biomarkers for locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

JV Machado Carvalho, V Dutoit, C Corrò, T Koessler - Cells, 2023 - mdpi.com
The treatment of locally advanced rectal cancer (LARC) requires a multimodal approach
combining neoadjuvant radiotherapy or chemoradiotherapy (CRT) and surgery. Predicting …

Exosomes: Small vesicles with important roles in the development, metastasis and treatment of breast cancer

L Meng, K Song, S Li, Y Kang - Membranes, 2022 - mdpi.com
Breast cancer (BC) has now overtaken lung cancer as the most common cancer, while no
biopredictive marker isolated from biological fluids has yet emerged clinically. After …

Perillyl alcohol, a pleiotropic natural compound suitable for brain tumor therapy, targets free radicals

AC Gomes, AL Mello, MG Ribeiro, DG Garcia… - Archivum Immunologiae …, 2017 - Springer
Monoterpenes such as limonene and perillyl alcohol (POH) are promising natural
compounds with pro-oxidant properties partly due to endoplasmic reticulum (ER) stress …

The effect of proinflammatory cytokines on the proliferation, migration and secretory activity of mesenchymal stem/stromal cells (Wj-mscs) under 5% O2 and 21% O2 …

A Wedzinska, A Figiel-Dabrowska… - Journal of Clinical …, 2021 - mdpi.com
Treatment with Mesenchymal Stem/Stromal Cells (MSCs) in clinical trials is becoming one of
the most-popular and fast-developing branches of modern regenerative medicine, as it is …

[HTML][HTML] Expression of MMP-14 and prognosis in digestive system carcinoma: a meta-analysis and databases validation

F Duan, Z Peng, J Yin, Z Yang, J Shang - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Background: The Matrix metalloproteinase-14 (MMP-14) expression has been shown to be
overexpressed in different cancers. However, there is no comprehensive quantitative …

Immunotherapy Using Oxygenated Water and Tumor‐Derived Exosomes Potentiates Antitumor Immune Response and Attenuates Malignancy Tendency in Mice …

N Pakravan, A Abbasi… - Oxidative Medicine and …, 2021 - Wiley Online Library
Breast cancer is one of the most common type of tumor and the leading cause of death in the
world's female population. Various therapeutic approaches have been used to treat tumors …