The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta‐analysis

H Zhang, J Chen, F Chen, W Que - Knee Surgery, Sports …, 2012 - Wiley Online Library
Purpose Studies have shown that tranexamic acid (TXA) reduces blood loss and transfusion
need in patients undergoing total knee arthroplasty (TKA). However, no single study has …

Tranexamic acid in hip and knee arthroplasty

JS Melvin, LS Stryker, RJ Sierra - JAAOS-Journal of the American …, 2015 - journals.lww.com
Perioperative blood loss is a significant concern for patients undergoing total joint
arthroplasty. A growing body of evidence has shown tranexamic acid (TXA) to be effective in …

Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis

R Gandhi, HMK Evans, SR Mahomed… - BMC research …, 2013 - Springer
Background Tranexamic acid (TXA) is an antifibrinolytic drug used as a blood-sparing
technique in many surgical specialties. The principal objective of our meta-analysis was to …

The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta‐analysis of 2720 cases

Z Wei, M Liu - Transfusion Medicine, 2015 - Wiley Online Library
Aims To evaluate the safety and efficacy of tranexamic acid (TXA) in total knee arthroplasty
(TKA) and total hip arthroplasty (THA). The specific endpoints assessed in this meta …

[PDF][PDF] 中国髋, 膝关节置换术围术期抗纤溶药序贯抗凝血药应用方案的专家共识

岳辰, 周宗科, 裴福兴, 翁习生… - 中华骨与关节 …, 2015 - 11871494.s21i.faimallusr.com
髋, 膝关节置换术常可伴随大量失血. 根据文献报道, 髋, 膝关节置换术围术期总失血量多在1000
ml 以上, 输血率高达30%~ 60%[1, 2]. 大量失血可增加患者的围术期风险和经济负担[3]. 髋 …

Evaluation of the efficacy and safety of tranexamic acid for reducing blood loss in bilateral total knee arthroplasty

JA Karam, MR Bloomfield, TM DiIorio, AM Irizarry… - The Journal of …, 2014 - Elsevier
Tranexamic acid (TA) has been reported to reduce blood loss after total joint arthroplasty;
however, the literature is sparse in evaluating its efficacy in simultaneous bilateral total knee …

Clinical value of tranexamic acid in unilateral and simultaneous bilateral TKAs under a contemporary blood-saving protocol: a randomized controlled trial

TK Kim, CB Chang, YG Kang, ES Seo, JH Lee… - Knee surgery, sports …, 2014 - Springer
Purpose Despite the documented blood-saving effects of tranexamic acid (TNA) in total knee
arthroplasty (TKA), the question whether clinical values of TNA are identical in unilateral and …

Effectiveness of oral tranexamic acid administration on blood loss after knee artroplasty: a randomized clinical trial

M Alipour, M Tabari, M Keramati, AM Zarmehri… - … and Apheresis Science, 2013 - Elsevier
Introduction Some studies have proved that Tranexamic acid infusion is associated with a
decrease in blood loss during and after surgery. Due to the availability of an oral form of the …

Reducing blood loss in simultaneous bilateral total knee arthroplasty: combined intravenous–intra-articular tranexamic acid administration. A prospective randomized …

F Karaaslan, S Karaoğlu, MU Mermerkaya, A Baktir - The Knee, 2015 - Elsevier
Background We asked whether tranexamic acid (TXA) administration could reduce blood
loss and blood transfusion requirements after simultaneous bilateral total knee arthroplasty …

Use of tranexamic acid in dynamic hip screw plate fixation for trochanteric fractures

RK Baruah, PJ Borah, R Haque - Journal of Orthopaedic …, 2016 - journals.sagepub.com
Purpose To evaluate perioperative blood loss and blood transfusion requirement in patients
who underwent dynamic hip screw plate fixation for a stable trochanteric fracture with or …