Electrospray mass spectrometry (ESI‐MS) in the study of metal–ligand solution equilibria

VB Di Marco, GG Bombi - Mass Spectrometry Reviews, 2006 - Wiley Online Library
In the 20 years, since the introduction of electrospray mass spectrometry (ESI‐MS), the use
of this technique in various fields of inorganic, organometallic, and analytical chemistry has …

Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside …

MP Mingeot-Leclercq, JL Décout - MedChemComm, 2016 - pubs.rsc.org
Hereunder, we highlight bacterial membrane anionic lipids as attractive targets in the design
of antibacterial drugs which can be effective against both Gram-positive and Gram-negative …

Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues

L Zimmermann, A Bussière, M Ouberai… - Journal of medicinal …, 2013 - ACS Publications
Aminoglycosides are antibiotic drugs that act through binding to rRNA. In the search for
antimicrobial amphiphilic aminoglycosides targeting bacterial membranes, we report here …

Multinuclear Nuclear Magnetic Resonance Spectroscopy Is Used to Determine Rapidly and Accurately the Individual pKa Values of 2-Deoxystreptamine, Neamine …

AH Alkhzem, TJ Woodman, IS Blagbrough - ACS omega, 2021 - ACS Publications
Unambiguous assignments have been made for each individual p K a value of the amino
group and guanidine substituents on 2-deoxystreptamine, neamine, neomycin …

Evaluation of alkali and alkaline earth metal cation selectivities of lariat ether amides by electrospray ionization mass spectrometry

SM Williams, JS Brodbelt… - Journal of the American …, 2003 - ACS Publications
Lariat ethers with pendant amide groups have shown promise as new ion sensors because
of their selectivity towards particular metal ions. In this study we report alkali and alkaline …

Antibiotic drugs aminoglycosides cleave DNA at abasic sites: shedding new light on their toxicity?

M Perigolo de Oliveira, JF Constant… - Chemical Research …, 2013 - ACS Publications
Abasic sites are probably the most common lesions in DNA resulting from the hydrolytic
cleavage of glycosidic bonds that can occur spontaneously and through DNA alkylation by …

NMR and amber analysis of the neamine pharmacophore for the design of novel aminoglycoside antibiotics

CA Andac, TC Stringfellow, U Hornemann… - Bioorganic …, 2011 - Elsevier
The dependence of the solution structure of neamine on pH was determined by NMR and
AMBER molecular dynamics methods at pD 3.3, pD 6.5, and pD 7.4 in D2O at 25° C. Unlike …

[引用][C] NMR ANALYSIS AND AMBER DESIGN OF NOVEL AMINOGLYCOSIDE ANTIBIOTICS

YAANMRA VE - 2010 - GAZI UNIVERSITY