Red blood cell (RBC) transfusion is common in critically ill, postsurgical, and posttrauma
patients in whom both systemic inflammation and immune suppression are associated with …

In some patients, the inflammatory‐immune response to surgical injury progresses to a
harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation …

Transfusion‐related immunomodulation (TRIM) in the intensive care unit (ICU) is difficult to
define and likely represents a complicated set of physiologic responses to transfusion …

Objective: The aim of this study was to evaluate the role of interleukin (IL)-6 pathways in
postoperative immune suppression and to assess the reversibility of this phenomenon …

Abstract The European Hematology Association (EHA) Roadmap for European Hematology
Research highlights major achievements in diagnosis and treatment of blood disorders and …

Laboratory techniques are now available that can monitor the perioperative immune
response and could be further developed to introduce personalized care pathways …

Surgery and other invasive procedures, which are routinely performed during general
anesthesia, may induce an inflammatory response in the patient. This inflammatory …

The advent of highly sensitive molecular diagnostic techniques has improved our ability to
detect viral pathogens leading to severe and often fatal infections that require admission to …

Point of care tests are emerging that allow monitoring of the perioperative immune response.
These could be further developed to introduce personalised care pathways. Consideration …

Background Postoperative peritonitis (POP) following gastrointestinal surgery is associated
with significant morbidity and mortality, with no clear management option proposed. The aim …